Susanne Staehlke | Cell-Biomaterial-Interaction | Best Researcher Award

Dr. Susanne Staehlke | Cell-Biomaterial-Interaction | Best Researcher Award

Rostock University Medical Center | Germany

Author Profile

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📚 EARLY ACADEMIC PURSUITS

Dr. Susanne Staehlke began her academic journey with a focus on Genetic and Microbiology at the University of Rostock, Germany, from 2000 to 2006. During this time, she specialized in signal transduction in Oncorhynchus mykiss (rainbow trout), which laid the foundation for her interest in molecular biology and cell signaling. She continued her studies at Rostock University Medical Center, where she earned her PhD in Cell Biology in 2014. Her doctoral research focused on the interaction between human osteoblasts and geometrically structured implant surfaces, specifically investigating cell architecture and signal transduction.

💼 PROFESSIONAL ENDEAVORS

Dr. Staehlke’s career as a scientist includes an extensive background in cell biology, biomaterials, and tissue engineering. After earning her PhD, she embarked on post-doctoral research that expanded her expertise into ophthalmology, where she focused on understanding cell responses to surface modifications for ocular applications. Her work in this area also involved collaborations with experts in various fields, including engineering, physics, chemistry, and medicine, to enhance biomaterial designs for clinical applications. Throughout her career, Dr. Staehlke has contributed to over 40 publications, and her work has made significant strides in the fields of biomaterials and regenerative medicine.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON Cell-Biomaterial-Interaction

Dr. Staehlke has made a profound impact in the fields of biomaterials, cell biology, and tissue engineering. Her primary research focus has been on optimizing cell-biomaterial interactions, particularly improving osteoblast responses to implant surfaces. By investigating physico-chemical surface modifications, such as plasma polymer coatings and topographical features, Dr. Staehlke’s work has advanced biomaterial design, enhancing cell behavior and implant integration. Additionally, her research in the integration of artificial intelligence (AI), machine learning, and big data analytics has enabled better prediction of cellular responses to various biomaterials. Her interdisciplinary approach has driven significant advancements in regenerative medicine, stem cell characterization, and biomedicines.

🌍 IMPACT AND INFLUENCE

Dr. Staehlke’s contributions to science have had a lasting influence on biomaterial innovation, tissue engineering, and regenerative medicine. Her work has led to groundbreaking advances in surface modifications for implants, improving both the functional and biological success of biomaterials. Dr. Staehlke has also been instrumental in enhancing the reproducibility of scientific research by advocating for rigorous data analysis methods and the development of open-source platforms for data management. Her interdisciplinary approach, which bridges cell biology with computational tools and engineering, has strengthened scientific rigor and fostered collaborations across diverse fields.

📑 ACADEMIC CITES

Dr. Staehlke’s work has garnered significant academic recognition, with over 40 publications in leading journals within the fields of biomaterials, cell biology, and tissue engineering. Her research is widely cited, contributing to the advancement of knowledge in cell-biomaterial interactions. She has a citation index of 506 and an h-index of 12, demonstrating the profound impact and influence of her scholarly contributions.

🏛️ LEGACY AND FUTURE CONTRIBUTIONS

Dr. Staehlke’s legacy in the scientific community will likely continue to grow as her research paves the way for new biomaterial technologies and therapeutic applications in regenerative medicine. Her integration of AI and big data into cell biology and biomaterials research ensures that her future contributions will further refine predictive models for cellular behavior, ultimately improving patient outcomes in tissue engineering and implantology. As she continues to collaborate with experts from various disciplines, Dr. Staehlke’s work promises to influence both academic research and clinical practice for years to come.

🤝 KEY COLLABORATIONS

Throughout her career, Dr. Staehlke has worked closely with interdisciplinary teams, including engineers, clinicians, data scientists, and materials scientists. Her research has benefited from collaborations in the fields of ophthalmology, biomaterials, and systems biology. These partnerships have led to innovative approaches for improving cell-biomaterial interactions and advancing technologies in regenerative medicine. Additionally, her work with AI and machine learning specialists has allowed her to optimize experimental data analysis, which has been essential for ensuring reproducibility and improving the predictive accuracy of her research findings.

🧑‍🔬 PROFESSIONAL MEMBERSHIPS

Dr. Staehlke holds memberships in several professional organizations, including the German Society for Biomaterials (DGBM), TERMIS (Tissue Engineering and Regenerative Medicine International Society), and the German Ophthalmology Society (DOG). These memberships reflect her commitment to staying at the forefront of developments in her field and engaging with a global network of researchers and professionals.

📊 RESEARCH DATA ANALYSIS AWARDS

Dr. Staehlke’s research has also been recognized in the field of data analysis, particularly for her innovative approaches in handling complex datasets related to cell-biomaterial interactions. This dedication to data integrity and reproducibility has earned her numerous accolades and collaborations with experts in scientific workflows and AI-powered data analysis tools.

📑 NOTABLE PUBLICATIONS 

Impact of Metal Ions on Cellular Functions: A Focus on Mesenchymal Stem/Stromal Cell Differentiation
    • Authors: Kirsten Peters, Susanne Staehlke, Henrike Rebl, Anika Jonitz-Heincke, Olga Hahn
    • Journal: International Journal of Molecular Sciences
    • Year: 2024
Suppressing Pro-Apoptotic Proteins by siRNA in Corneal Endothelial Cells Protects against Cell Death
    • Authors: Susanne Staehlke, Siddharth Mahajan, Daniel Thieme, Peter Trosan, Thomas A. Fuchsluger
    • Journal: Biomedicines
    • Year: 2024
Cold Atmospheric Pressure Plasma-Activated Medium Modulates Cellular Functions of Human Mesenchymal Stem/Stromal Cells In Vitro
    • Authors: Olga Hahn, Tawakalitu Okikiola Waheed, Kaarthik Sridharan, Thomas Huemerlehner, Susanne Staehlke, Mario Thürling, Lars Boeckmann, Mareike Meister, Kai Masur, Kirsten Peters
    • Journal: International Journal of Molecular Sciences
    • Year: 2024
The Impact of Ultrashort Pulse Laser Structuring of Metals on In-Vitro Cell Adhesion of Keratinocytes
    • Authors: Susanne Staehlke, Tobias Barth, Matthias Muench, Joerg Schroeter, Robert Wendlandt, Paul Oldorf, Rigo Peters, Barbara Nebe, Arndt-Peter Schulz
    • Journal: Journal of Functional Biomaterials
    • Year: 2024
Short-Time Alternating Current Electrical Stimulation and Cell Membrane-Related Components
    • Authors: Maren E. Buenning, Meike Bielfeldt, Barbara Nebe, Susanne Staehlke
    • Journal: Applied Sciences
    • Year: 2024

Nabras Al-Mahrami | Proteomics | Best Researcher Award

Mr. Nabras Al-Mahrami | Proteomics | Best Researcher Award

Oman College of Health Sciences, Oman

Author Profiles 📚

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Early Academic Pursuits 🎓

Mr. Nabras Al-Mahrami’s academic journey has been marked by a strong foundation in molecular medicine and bioinformatics. After completing his BSc in Medical Laboratory Science at Oman College of Health Sciences in 2018, he pursued an MSc in Molecular Medicine (Bioinformatics) at the Cyprus Institute of Neurology and Genetics in Cyprus, graduating in 2022. His research project, titled “Bioinformatics approach to related genetic variants with functionality, phenotype, and pathogenicity,” underscores his deep interest in understanding the genetic basis of diseases through bioinformatics techniques. This academic background enabled him to merge laboratory science with computational biology seamlessly.

Professional Endeavors 🧬

Mr. Al-Mahrami has developed a strong professional profile, especially in bioinformatics, through his roles at Oman College of Health Sciences and the National Genetic Center. As a Bioinformatician at the Royal Hospital in Muscat from 2018 to 2024, he played a key role in genomics data analysis, developing pipelines for whole genome sequencing (WGS), whole exome sequencing (WES), and target panel analysis. His work also spanned Genome-Wide Association Studies (GWAS), Gene Set Enrichment Analysis (GSEA), RNA-seq analysis, and proteomics data analysis, demonstrating his broad and diverse expertise in the molecular biology and bioinformatics fields.

Contributions and Research Focus 🔬

Mr. Al-Mahrami’s research has greatly contributed to the field of bioinformatics, particularly in genetic variant analysis, phenotypic predictions, and understanding the pathogenicity of diseases. His use of advanced tools like machine learning, molecular docking, and network interaction analysis in the development of bioinformatics tools has further enhanced the precision of genomic research. His impactful research involves bridging the gap between bioinformatics, molecular genetics, and clinical applications, fostering advancements in precision medicine.

Impact and Influence 🌍

Through his work, Mr. Al-Mahrami has influenced bioinformatics research not only in Oman but globally. His involvement in high-profile conferences, such as the 5th Congress of Reproductive Genetics and the Precision Med Exhibit and Summit 2023, has allowed him to share his insights on cutting-edge genetic technologies and their clinical applications. His academic contributions have positioned him as a key figure in applying bioinformatics approaches to real-world medical challenges.

Academic Cites 📚

Mr. Al-Mahrami has contributed significantly to academic advancements. His research and presentations have been featured at various scientific conferences and workshops, such as the Gene Set Enrichment Analysis Workshop hosted by the Swiss Bioinformatics Institute. His academic works and insights into genetic technologies are widely cited and discussed in the bioinformatics and medical communities, particularly regarding the potential of AI-driven bioinformatics tools in healthcare.

Technical Skills 💻

Mr. Al-Mahrami possesses advanced technical skills essential for modern bioinformatics. His proficiency in R (RStudio) and Python programming allows him to handle large datasets and perform complex analyses, while his experience with Linux OS and HPC ensures that his computational work is efficient and scalable. Additionally, his knowledge in CSS and JavaScript aids in the development of user-friendly bioinformatics tools and applications.

Teaching Experience👨‍🏫

In 2024, Mr. Al-Mahrami took on the role of Academic Faculty in Bioinformatics at Oman College of Health Sciences, where he teaches Principles of Bioinformatics, covering both theoretical and practical modules, and Laboratory Management. His ability to impart knowledge to students helps shape the next generation of bioinformaticians, ensuring they are equipped with both theoretical insights and hands-on experience in the field. His passion for education extends beyond the classroom, influencing students to pursue careers in bioinformatics and molecular medicine.

Legacy and Future Contributions 🌟

Looking forward, Mr. Al-Mahrami’s journey is marked by his commitment to expanding bioinformatics research and education in Oman and beyond. His work in genomic data analysis, AI integration, and bioinformatics tools development lays the groundwork for future innovations in personalized medicine. His legacy will likely include contributing to groundbreaking research and training future generations of bioinformaticians, particularly in regions with emerging biomedical research landscapes. With his continued involvement in both academia and research, his influence on the scientific community is poised to grow, fostering a deeper understanding of the genetic basis of diseases and improving patient care globally.

Top Noted Publications 📖

Exploring advanced genomic and immunoinformatics techniques for identifying drug and vaccine targets against SARS-CoV-2
    • Authors: Syed Luqman Ali, Awais Ali, Waseef Ullah, Abdulaziz Alamri, Elham Mohammed Khatrawi, Gulzira Sagimova, Aigul Almabayeva, Farida Rakhimzhanova, Gulsum Askarova, Fatima Suleimenova et al.
    • Journal: Journal of Genetic Engineering and Biotechnology
    • Year: 2024
In-silico and in-vitro studies to identify potential inhibitors of SARS-CoV-2 spike protein from Omani medicinal plants
    • Authors: Nabras Al-Mahrami, Smitha Sunil Kumaran Nair, Adhra Al Mawali, Raja-Mohamed Beema Shafreen, Saeed Ullah, Sobia Ahsan Halim, Ahmed Al-Harrasi, Nallusamy Sivakumar
    • Journal: Heliyon
    • Year: 2024
Bioinformatics Approach is Unraveling Potential Crosstalk between Cytomegalovirus and Epilepsy
    • Authors: Salim Al Rashdi, Nabras Al-Mahrami
    • Journal: Preprint
    • Year: 2024
PlantMedOman: an online database for Oman’s medicinal plants
    • Authors: Department of Computing and Electronics Engineering, Middle East College, Sultanate of Oman; Smitha Sunil Kumaran Nair; Aqsa Bibi; Nabras Al-Mahrami; Piyusha Mahesh Satam; Alya Al Farsi et al.
    • Journal: Bioinformation
    • Year: 2024