Dolores Di Vizio | Big Data Analytics | Best Researcher Award

Prof Dr. Dolores Di Vizio | Big Data Analytics | Best Researcher Award

Cedars-Sinai Medical Center | United States

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👩‍⚕️ Current Positions

Prof. Dr. Dolores Di Vizio currently serves as a Professor of Surgery, Pathology & Laboratory Medicine, and Biomedical Sciences at Cedars-Sinai Medical Center, a position she has held since 2018. She also holds the title of Co-Director of the Cancer Biology Program at Cedars-Sinai since 2022, where she plays a pivotal role in driving forward interdisciplinary cancer research and translational initiatives.

✅ Suitability Summary

Prof. Di Vizio is an internationally recognized physician-scientist with a strong background in pathology, molecular biology, and oncology. Her career reflects a seamless integration of clinical insight and scientific innovation, particularly in the study of prostate and ovarian cancers. With leadership experience in multiple international societies, active roles in peer-review panels, and a robust publication and funding record, she is well-positioned to lead high-impact translational research. Her expertise in extracellular vesicles, large oncosomes, molecular diagnostics, and tumor microenvironment makes her a valuable asset to the scientific and medical community.

🎓 Education & Experience

Prof. Di Vizio earned her MD from the University of Naples Federico II in 1994, followed by a Residency in Anatomic Pathology at the same institution. She later obtained her PhD jointly from the University of Naples Federico II and Albert Einstein College of Medicine in New York in 2003. Her postdoctoral work included significant research fellowships at Dana-Farber Cancer Institute, Boston Children’s Hospital, and Harvard Medical School. Academically, she has held faculty positions at Harvard Medical School and Cedars-Sinai, where she advanced from Assistant to Associate to full Professor. Additionally, she has served as Visiting Professor at top international institutions including POSTECH (South Korea), University of Trento (Italy), and Sapienza University (Rome).

📜 Professional Development

Dr. Di Vizio has contributed significantly to institutional leadership and mentorship at Cedars-Sinai through roles on the Graduate Program Thesis Committee, Faculty Recruitment Committees, and the Graduate Education Governance Committee. She has also been deeply involved in organizing scientific symposiums and steering faculty searches in Urology, Pathology, and Radiology. Nationally and internationally, she has served as a grant reviewer for organizations such as the NIH, Department of Defense (CDMRP), Prostate Cancer UK, and the Israeli Ministry of Science. Her work on study sections and review panels reflects her thought leadership in oncology and translational medicine.

🔬 Research Focus

Prof. Di Vizio’s research centers on the biology and clinical translation of extracellular vesicles, particularly large oncosomes, in cancer progression. Her lab investigates the molecular mechanisms of EV-mediated tumor communication, explores exosomal biomarkers for cancer diagnostics, and studies the role of mitochondrial DNA haplogroups in treatment response. She is also engaged in collaborative projects focused on exosomal SPHK1 in ovarian cancer and the development of novel liquid biopsy tools.

🏆 Honors & Awards

Among her many accolades, Prof. Di Vizio was awarded the K99-R00 NIH Pathway to Independence Award, the SBUR Research Scholar Award, and the UCLA SPORE in Prostate Cancer Career Development Award. She has been an active and elected member of the Board of Directors of the International Society of Extracellular Vesicles (ISEV), where she also served as Chair of Communications and Membership. In 2023 and 2024, she chaired key ISEV conferences and workshops, and in 2025 she will chair the Gordon Research Conference on RNA Nanotechnology. Recently, she was also named the winner of the EV Super-Resolution Competition and Co-Lead for ISEV’s Blood Task Force Education & Outreach Working Group.

📚 Selected Publication

 Emerin Dysregulation Drives the Very-Small-Nuclear Phenotype and Lineage Plasticity That Associate with a Clinically Aggressive Subtype of Prostate Cancer

Authors: L. Zhang, P. Teng, K.A. Cavassani, … J. Chen, E.M. Posadas
Journal: Clinical Cancer Research
Year: 2025

A class of large cell-like extracellular vesicles

Authors: C. D’Souza-Schorey, D. Di Vizio
Journal: Nature Cell Biology
Year: 2025

Mechanisms governing lineage plasticity and metabolic reprogramming in cancer

Authors: L.M. Perez, S.V. Venugopal, A.S. Martin, … D. Di Vizio, M.R. Freeman
Journal: (Journal not specified; likely a review article in a high-impact oncology journal)
Year: 2025

ONECUT2 acts as a lineage plasticity driver in adenocarcinoma as well as neuroendocrine variants of prostate cancer

Authors: C. Qian, Q. Yang, M. Rotinen, … S.Y. You, M.R. Freeman
Journal: Nucleic Acids Research
Year: 2024

Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution

Authors: A.K. von Lersner, F. Fernandes, P.M. Ozawa, … D. Di Vizio, A. Zijlstra
Journal: ACS Nano
Year: 2024

Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis

Authors: W. Fan, D. Cao, B. Yang, … H. Yang, S.C. Lu
Journal: Journal of Hepatology
Year: 2024

 Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Authors: J.A. Welsh, D.C.I. Goberdhan, L.R. O’Driscoll, … S.E. Andaloussi, J.D. Anderson
Journal: Journal of Extracellular Vesicles
Year: 2024

 International Society for Extracellular Vesicles workshop. QuantitatEVs: Multiscale analyses, from bulk to single extracellular vesicle

Authors: M. Basso, A. Gori, C. Nardella, … M. Cretich, F. Demichelis
Journal: Journal of Extracellular Biology
Year: 2024

 Blebs and former blebs: From surface protrusions to extracellular vesicles in cancer signalling, anoikis resistance and beyond

Authors: D. Di Vizio, M. Schoppet, A.T. Weeraratna, K.W. Witwer
Journal: Journal of Extracellular Biology
Year: 2023

 Integrating extracellular vesicle and circulating cell-free DNA analysis using a single plasma aliquot improves the detection of HER2 positivity in breast cancer patients

Authors: V. Mugoni, Y. Ciani, O. Quaini, … C. Nardella, F. Demichelis
Journal: Journal of Extracellular Biology
Year: 2023

Pedro Sousa | Atrial fibrillation ablation | Best Researcher Award

Dr. Pedro Sousa | Atrial fibrillation ablation | Best Researcher Award

Centro Hospitalar e Universitário de Coimbra | Portugal

PROFILE VERIFIED

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👋 INTRODUCTION

Dr. Pedro Alexandre Sousa is a highly skilled Portuguese cardiologist specializing in electrophysiology, currently practicing at Centro Hospitalar e Universitário de Coimbra. With over a decade of experience in cardiology and arrhythmia management, Dr. Sousa has built a career grounded in clinical excellence, academic research, and technological advancement. His unwavering commitment to improving patient outcomes through innovation makes him a respected figure in both national and international cardiology communities.

🎓 EARLY ACADEMIC PURSUITS

Dr. Sousa embarked on his medical journey at the Lisbon Faculty of Medicine, earning his MD between 2001 and 2007. His early training included a general internship in the Azores at Santo Espírito Hospital in 2008. Dedicated to continuous learning, he pursued a postgraduate degree in Sports Medicine in Lisbon (2009–2010) and later served as an invited assistant in Biomedical Sciences at the University of Algarve, where he taught organ systems and function.

💼 PROFESSIONAL ENDEAVORS

After completing his cardiology residency at Faro Hospital (2009–2014), Dr. Sousa sought specialized training in invasive electrophysiology at Santa Cruz Hospital in Lisbon, followed by prestigious international fellowships in France—Clinique Pasteur in Toulouse and Clinique Saint Pierre in Perpignan. Since 2016, he has served as a Consultant Cardiologist and Electrophysiologist at CHUC Coimbra, performing complex ablations, S-ICD and Left Bundle Pacing implantations, and using advanced systems like CARTO, Ensite NavX, and Medtronic cryoablation.

🧪 CONTRIBUTIONS AND RESEARCH FOCUS

Dr. Sousa’s work has significantly impacted arrhythmia diagnostics and treatment, particularly in atrial fibrillation, ventricular arrhythmias, and mapping-guided ablation strategies. He has expertise in cutting-edge tools such as Pattern Matching Filters, Multielectrode Mapping, and HD Coloring. A certified EHRA specialist (Level 2), he is also involved in proctoring and education for Abbott, Biosense Webster, Boston Scientific, and Medtronic, showcasing his role as a technology-driven educator and clinical expert.

🌍 IMPACT AND INFLUENCE

Beyond clinical duties, Dr. Sousa has been instrumental in multiple international clinical trials and registries, including RED-HF, ATMOSPHERE, GLORIA-AF, and EURObservational AF studies. In Portugal, he has contributed to studies like SINCRONE and the National Registry of Acute Coronary Syndromes. His influence is further seen in his contributions to scientific advisory boards, review panels, and conference organizing committees, enhancing the field’s growth across Europe.

📚 ACADEMIC CITATIONS AND PUBLICATIONS

With 38 peer-reviewed publications19 as first author—and over 100 scientific presentations, Dr. Sousa is a prolific contributor to cardiology literature. Notable works include studies published in Europace, International Journal of Cardiology, JACC EP, and Journal of Cardiovascular Electrophysiology. His papers frequently explore ablation index strategies, PVC mapping, and coherent mapping for atrial flutter, offering valuable insights into real-world electrophysiological practice.

🏆 HONORS & AWARDS

Dr. Sousa holds elite certifications such as EHRA Level 2 Electrophysiology Specialist and Portuguese Electrophysiology Certification. He is a member of the European Society of Cardiology (ESC), the Portuguese Society of Cardiology, and the Portuguese Association of Arrhythmia, Pacing & Electrophysiology. These memberships reflect his standing as a recognized leader in the cardiovascular community, both academically and clinically.

🚀 LEGACY AND FUTURE CONTRIBUTIONS

Dr. Sousa’s ongoing contributions to the field of electrophysiology include not just patient care, but also research innovation and medical education. With a strong foundation in clinical mapping, ablation, and digital EP techniques, he is expected to play a key role in the evolution of AI-assisted electrophysiology and minimally invasive therapies. His legacy is one of precision, progress, and passionate dedication to arrhythmia treatment.

✉️ FINAL NOTE

Dr. Pedro Alexandre Sousa continues to lead with a combination of technical mastery, academic rigor, and collaborative spirit. Whether in the lab, clinic, or lecture hall, his contributions are shaping the future of electrophysiology.

📚 SELECTED PUBLICATIONS

Catheter ablation for atrial fibrillation: results from a European Survey
Heart Rhythm
2025-05 | Journal article
Contributors: Pedro A. Sousa; Christian-Hendrik Heeger; Sérgio Barra; Vishal Luther; Johannes Steinfurt; Juan Fernandez-Armenta; John Silberbauer

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Crossref
Role of Octaspline Multielectrode Catheter and Unipolar Reference Location for Premature Ventricular Contraction Ablation
Journal of Cardiovascular Electrophysiology
2025-05 | Journal article
Contributors: Pedro A. Sousa; Carolina Saleiro; Sérgio Barra; Inês Fonseca; Luís Elvas; John Silberbauer; Lino Gonçalves

Source:check_circle

Crossref
Can Pre-Ablation Biomarkers Be Used to Predict Arrhythmia Recurrence after Ablation Index-Guided Atrial Fibrillation Ablation?
Arquivos Brasileiros de Cardiologia
2024 | Journal article
Contributors: Andreia Palma; Pedro A. Sousa; Carolina Saleiro; Sérgio Barra; Natália António; Luis Adão; João Primo; Ana Lebreiro; Paulo Fonseca; Luís Elvas et al.

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Crossref
Os Biomarcadores podem ser Utilizados para Prever Recorrência de Arritmia após a Ablação de Fibrilação Atrial Guiada pelo Ablation-Index?
Arquivos Brasileiros de Cardiologia
2024 | Journal article
Contributors: Andreia Palma; Pedro A. Sousa; Carolina Saleiro; Sérgio Barra; Natália António; Luis Adão; João Primo; Ana Lebreiro; Paulo Fonseca; Luís Elvas et al.

Source:check_circle

Crossref
Real-world assessment of multipolar and point-by-point mapping for premature ventricular contraction ablation
Europace
2024-06-03 | Journal article
Contributors: Pedro A Sousa; Johanna Tonko; Dagmara Dilling-Boer; Sérgio Barra; Anna-Sophie Eberl; Borka Pezo; Nuno Cortez-Dias; Ziad Khoueiry; Paulo Medeiros; Moisés Rodríguez-Mañero et al.