Wuzheng Zhu | Qualitative Research | Research Excellence Award

Dr. Wuzheng Zhu | Qualitative Research | Research Excellence Award

College of Life Sciences | China

Dr. Wuzheng Zhu is a regenerative medicine researcher, specializing in mitochondrial biology, cellular repair, and stem‑cell therapies. He earned his Ph.D. in Biochemistry and Molecular Biology from Sichuan University’s Regenerative Medicine Research Center (West China Hospital). Currently based in the Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Changsha, his work delves into the molecular mechanisms underlying mitochondrial homeostasis, particularly in the context of acute kidney injury and cardiovascular diseases. His lab combines biochemistry, molecular and cellular biology, drug screening, and mouse models to identify and manipulate mitochondrial regulation and repair pathways. Dr. Zhu has published extensively, with 5 documents, 306 citations, and an h‑index of 5, including influential studies on mesenchymal stem cell–mediated protection via mitophagy, mitochondrial dynamics in endothelial injury, lysosomal dysfunction in macrophage polarization, and suppression of ER stress in vascular cells. He has also investigated dietary intervention in piglet gut development. He is a recipient of the prestigious TTS‑CTRMS Scientific Congress Award in 2017. His research offers significant translational potential, aiming to harness mitochondrial modulation and stem-cell strategies for therapeutic intervention in metabolic and cardiovascular conditions.

Profile : Scopus

Featured Publications

Wei, J., Mao, R., Chen, Y., Si, K., Li, Y., Li, J., & Zhu, W. (2025). “MSCs ameliorates hyperglycemia-induced endothelial injury through modulation of mitochondrial dynamics” in Cell Death & Disease, 16(1), 832.

Mao, R.W., He, S.P., Lan, J.G., & Zhu, W.Z. (2022). “Honokiol ameliorates cisplatin‐induced acute kidney injury via inhibition of mitochondrial fission” in British Journal of Pharmacology.

Zhu, W., Yuan, Y., Liao, G., Li, L., Liu, J., Chen, Y., et al. (2018). “Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy” in Cell Death & Disease, 9(8), 1–17.

Yuan, Y., Chen, Y., Peng, T., Li, L., Zhu, W., Liu, F., et al. (2019). “Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition” in Clinical Science, 133(15), 1759–1777.

Luo, R., Li, L., Liu, X., Yuan, Y., Zhu, W., Li, L., et al. (2020). “Mesenchymal stem cells alleviate palmitic acid-induced endothelial-to-mesenchymal transition by suppressing endoplasmic reticulum stress” in American Journal of Physiology-Endocrinology and Metabolism, 319(6), E961–E980.

Zhifen Chen | Public Health Analytics | Best Researcher Award

Dr. Zhifen Chen | Public Health Analytics | Best Researcher Award

German Heart Center, TUM University Hospital, Technical University of Munich (TUM) | Germany

Dr. Zhifen Chen is an Independent Junior Group Leader at the German Heart Center, Technical University of Munich, specializing in experimental cardiology. She earned her Bachelor’s degree in Life Sciences from Hubei Normal University and a Master of Science from Tsinghua University. Dr. Chen completed her PhD at the Technical University of Munich with a summa cum laude distinction, focusing on human iPSC-derived cardiomyocytes for cardiac disease modeling, therapeutic discovery, and safety pharmacology. She pursued postdoctoral research at Harvard University and the Beth Israel Deaconess Medical Center, contributing to functional genomics, CRISPR-based screening, and cardiovascular disease studies. Her research focuses on the genetics and molecular mechanisms of coronary artery disease, adipose tissue biology, insulin resistance, and cardiovascular precision medicine. Dr. Chen has secured multiple competitive grants, including from the DFG, DZHK, and international cardiovascular research partnerships. She has received numerous awards and honors, such as PhD summa cum laude, international travel awards, and conference prizes. She actively supervises postdoctoral researchers, PhD, MD, Master, and Bachelor students, and contributes to scientific communities as a reviewer, consortium member, and workshop organizer. Dr. Chen’s work integrates genome editing, transcriptomics, and advanced in vitro models to identify novel therapeutic targets, advancing cardiovascular research and translational medicine.

Profile : Orcid

Featured Publications

von Scheidt, M., Adkar, S. S., Krefting, J., Hoermann, G., Meggendorfer, M., Bauer, S., Mitchell, S., Pugach, I., Friess, C., Ma, A., et al. (2025). “Clonal Haematopoiesis of Indeterminate Potential and Mortality in Coronary Artery Disease.” European Heart Journal.

Xu, C., Nie, X., Chen, Z., Qu, J. Z., & Wang, D. (2025). “Stenotic Left Atrioventricular Valve after Atrioventricular Septal Defect Repair: A Distinct Surgical Phenotype.” The Journal of Thoracic and Cardiovascular Surgery.

Chen, Z., Li, S., Song, X., Diagel, A., Li, L., Moggio, A., Li, Z., Chen, Y., Dang, T., Li, M., et al. (2025). “An Interplay of Non-Coding RNAs Regulates CDH13 Expression and Affects Endothelial Function and Coronary Artery Disease Risk.” Preprint.

Byers, P., Kellerer, T., Li, M., Chen, Z., Huser, T., & Hellerer, T. (2025). “Super-Resolution Upgrade for Deep Tissue Imaging Featuring Simple Implementation.” Nature Communications.

Sanin, V., Schmieder, R. S., Koenig, W., Li, L., Schunkert, H., & Chen, Z. (2025). “Rolle der Genetik in der Präzisionsmedizin der Koronaren Herzkrankheit.” Herz.