Prof. Hao Gao | Healthcare Data Analysis | Best Researcher Award
Jinan University, China
Author Profiles
👨‍🎓 Early Academic Pursuits
Prof. Hao Gao began his academic journey with a strong foundation in natural medicine chemistry. He received his PhD from Shenyang Pharmaceutical University in 2005, focusing on the chemistry of natural medicines. This early academic work set the stage for his future contributions to the field of Traditional Chinese Medicine (TCM). After completing his doctorate, he further honed his expertise through postdoctoral training at Tsinghua University (2006-2008), a renowned institution that significantly influenced his approach to scientific research and innovation.
đź’Ľ Professional Endeavors and Leadership
Prof. Gao’s professional trajectory has been marked by leadership roles that have shaped his career and the direction of his research. In 2008, he joined the Institute of Traditional Chinese Medicine & Natural Products at Jinan University as a faculty member. Since 2013, he has been a professor at the university and, in 2016, assumed the position of Head of the Institute of Traditional Chinese Medicine & Natural Products. In 2020, he expanded his administrative responsibilities by taking on the role of Director of the Science and Technology Department at Jinan University. Prof. Gao’s leadership has been pivotal in fostering multidisciplinary collaborations and advancing research initiatives in natural medicine chemistry.
🔬 Contributions and Research Focus
Prof. Gao’s research is primarily centered on natural medicine chemistry, with a particular focus on the active compounds and technological advancements related to Traditional Chinese Medicine (TCM). His work is dedicated to exploring under-researched medicinal materials like Lycium barbarum, Angelica sinensis, and Ophiocordyceps sinensis, which are central to TCM practices. Prof. Gao has made significant strides in identifying bioactive substances and developing novel drugs derived from TCM. Notably, his research has led to the discovery of four classes of lead compounds for anti-dementia drugs, all characterized by independent intellectual property rights.
🌍 Impact and Influence
Prof. Gao’s impact extends beyond academia, with substantial contributions to the modernization of TCM and drug development. His collaborations with international experts, such as Professor Ikuro Abe from the University of Tokyo, have facilitated the establishment of the International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development, a joint initiative between China’s Ministry of Education and Jinan University. This partnership exemplifies Prof. Gao’s influence on global TCM research and highlights his role in pushing the boundaries of natural product-based drug development.
đź“š Academic Citations and Recognition
Prof. Gao’s research has gained widespread recognition, reflected in his 4100 citations across various SCI journals. His work has significantly contributed to the advancement of natural medicine chemistry and TCM, making him a highly influential figure in the field. His numerous publications, with 195 journal articles and one book published, continue to shape research in TCM and pharmacology. Moreover, his leadership as an editor for the China Section of the Journal of Natural Medicines and as an editorial board member for Acta Pharmaceutica Sinica B highlights his prominence in the academic community.
🛠️ Technical Skills and Innovations
Prof. Gao’s technical expertise spans various critical areas, including the extraction, isolation, and characterization of bioactive compounds from TCM. His innovations in pharmacodynamic constituents of TCM have contributed to the discovery of novel drug candidates, some of which are in the process of patenting. With over 71 patents published or pending, Prof. Gao stands at the forefront of translating TCM practices into scientifically validated therapeutic solutions. His lab continues to focus on critical technologies that aim to enhance the efficacy and safety of TCM-derived medicines.
👩‍🏫 Teaching Experience
In addition to his research, Prof. Gao has been an integral part of the academic community at Jinan University, mentoring and guiding students in the fields of pharmacology and natural medicine chemistry. His teaching philosophy integrates cutting-edge research with practical applications in TCM, ensuring that his students are well-equipped to pursue careers in both academia and industry. As a mentor, Prof. Gao has inspired numerous graduate students and postdoctoral researchers, many of whom have gone on to make their own contributions to TCM and drug development.
🌱 Legacy and Future Contributions
Prof. Gao’s legacy is built on his pioneering work in natural medicine chemistry and the modernization of Traditional Chinese Medicine. His research continues to influence the field, with ongoing projects that promise to uncover more bioactive compounds and therapeutic agents. As his career progresses, Prof. Gao remains committed to advancing TCM through innovation and interdisciplinary collaboration. His future work will likely expand the global recognition of TCM-based drugs, pushing the boundaries of natural product drug discovery and pharmacology for the betterment of human health.
🌟 Professional Memberships and Editorial Roles
Prof. Gao is an active member of the China Association of Chinese Medicine, where he serves as Vice Chairperson of the Youth Work Committee. His role in professional societies and editorial boards, including his editorial positions in high-impact journals, underscores his authority in the fields of natural products and biosynthesis. His leadership extends to guiding the next generation of researchers and practitioners in these fields.
đź“– Top Noted PublicationsÂ
Functional and structural dissection of glycosyltransferases underlying the glycodiversity of wolfberry-derived bioactive ingredients lycibarbarspermidines
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- Authors: Li, S.-Y., Wang, G.-Q., Long, L., Abe, I., Gao, H.
- Journal: Nature Communications
- Year: 2024
Identification of three novel P450 enzymes involved in the oxidative modification of a newly discovered fusicoccane diterpene
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- Authors: Dong, L., Liu, J.-Y., Wang, G.-Q., Hu, D., Gao, H.
- Journal: Bioorganic Chemistry
- Year: 2024
Targeted Discovery of a Natural ortho-Quinone Methide Precursor and Green Generation of Its Oligomers
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- Authors: Wang, X.-X., Deng, B.-Q., Ouyang, Z.-Q., Yao, X.-S., Gao, H.
- Journal: Journal of Natural Products
- Year: 2024
A Functional Switch Between Asperfumene and Fusicoccadiene Synthase and Entrance to Asperfumene Biosynthesis through a Vicinal Deprotonation-Reprotonation Process
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- Authors: Liu, J.-Y., Lin, F.-L., Taizoumbe, K.A., Gao, H., Dickschat, J.S.
- Journal: Angewandte Chemie – International Edition
- Year: 2024
Mechanistic characterisation of a fungal fusicoccane-type diterpene synthase involved in the biosynthesis of talaro-7,13-diene
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- Authors: Lin, F.-L., Taizoumbe, K.A., Wang, Y.-X., Gao, H., Dickschat, J.S.
- Journal: Organic and Biomolecular Chemistry
- Year: 2024