Assist Prof Dr. Cheng-Yuan Lai | Neurophysiology | Best Researcher Award
Assist Prof Dr. Cheng-Yuan Lai at Institute of Biomedical Sciences/MacKay Medical College, Taiwan
👨🎓 Profile
🧠 Academic Background
Dr. Cheng-Yuan Lai’s academic foundation is rooted in advanced studies of neurophysiology and related disciplines, providing a strong basis for his research into complex physiological processes.
🎓 Education
- Ph.D. in Veterinary Medicine: Specialized in neurophysiology and pain mechanisms, equipping Dr. Lai with deep insights into the physiological and pathological aspects of his research focus.
💼 Professional Experience
- Assistant Professor (Institute of Biomedical Sciences, MacKay Medical College): Leading research and education in neurophysiology and pain pathophysiology.
- Postdoctoral Fellow (Department of Medicine, MacKay Medical College): Conducted advanced research on pain mechanisms and urinary tract physiology.
- Adjunct Assistant Professor (Department of Nursing, MacKay Medical College & Department of Biotechnology, Ming Chuan University): Contributed to interdisciplinary teaching and research collaborations.
🔬 Research Interests
- Neurophysiology: Exploring the functions and disorders of the nervous system, including the mechanisms of pain and sensory processing.
- Lower Urinary Tract Physiology: Investigating the physiological and pathological aspects of urinary tract functions, with a focus on bladder compliance and urinary incontinence.
- Pain Pathophysiology: Analyzing the molecular and epigenetic mechanisms contributing to chronic pain conditions, including neuropathic pain and its management.
- Epigenetic Modifications: Studying how genetic expression changes contribute to pain and urinary disorders, and how these changes can be targeted for therapeutic interventions.
📖 Publications
Thermodynamic Work of High-Grade Uterine Prolapse Patients Undergoing Transvaginal Mesh Repair with Total Hysterectomy
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- Authors: Hui-Hsuan Lau, Cheng-Yuan Lai, Ming-Chun Hsieh, Hsien-Yu Peng, Dylan Chou, Tsung-Hsien Su, Jie-Jen Lee, Tzer-Bin Lin
- Journal: Bioengineering
- Year: 2024
- DOI: 10.3390/bioengineering11090875
Methylone Produces Antidepressant-Relevant Actions and Prosocial Effects
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- Authors: Zhenlong Li, Hsien-Yu Peng, Chau-Shoun Lee, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Han-Fang Wu, Lih-Chyang Chen, Mei-Ci Chen, Dylan Chou
- Journal: Neuropharmacology
- Year: 2024
MicroRNA-489-3p Attenuates Neuropathic Allodynia by Regulating Oncoprotein DEK/TET1-Dependent Epigenetic Modification in the Dorsal Horn
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- Authors: Cheng-Yuan Lai, Ming-Chun Hsieh, Chou-Ming Yeh, Po-Sheng Yang, Jen-Kun Cheng, Hsueh-Hsiao Wang, Kuan-Hung Lin, Siao-Tong Nie, Tzer-Bin Lin, Hsien-Yu Peng
- Journal: Neuropharmacology
- Year: 2022
Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia
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- Authors: Cheng-Yuan Lai, Ming-Chun Hsieh, Yu-Cheng Ho, Hsueh-Hsiao Wang, Dylan Chou, Yang-Cheng Wen, Po-Sheng Yang, Jen-Kun Cheng, Hsien-Yu Peng
- Journal: The Journal of Neuroscience
- Year: 2018
Spinal Fbxo3-Dependent Fbxl2 Ubiquitination of Active Zone Protein RIM1α Mediates Neuropathic Allodynia Through CaV2.2 Activation
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- Authors: Cheng-Yuan Lai, Yu-Cheng Ho, Ming-Chun Hsieh, Hsueh-Hsiao Wang, Jen-Kun Cheng, Yat-Pang Chau, Hsien-Yu Peng
- Journal: The Journal of Neuroscience
- Year: 2016
Fbxo3-Dependent Fbxl2 Ubiquitination Mediates Neuropathic Allodynia Through the TRAF2/TNIK/GluR1 Cascade
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- Authors: Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Jen-Kun Cheng, Yat-Pang Chau, Ting Ruan, Gin-Den Chen, Hsien-Yu Peng
- Journal: The Journal of Neuroscience
- Year: 2015
VPS26A–SNX27 Interaction-Dependent mGluR5 Recycling in Dorsal Horn Neurons Mediates Neuropathic Pain in Rats
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- Authors: Tzer-Bin Lin, Cheng-Yuan Lai, Ming-Chun Hsieh, Hsueh-Hsiao Wang, Jen-Kun Cheng, Yat-Pang Chau, Gin-Den Chen, Hsien-Yu Peng
- Journal: The Journal of Neuroscience
- Year: 2015