Prof. Dr. Yan Peng is a distinguished researcher in genetic testing and molecular genetics, currently serving as Ph.D. and Master’s supervisor, as well as Research Secretary at the School of Medicine, Fuyang Normal University. Dr. Peng earned a Ph.D. (2022) and M.S. (2018) from the University of Chinese Academy of Sciences and has been a faculty member at Fuyang Normal University since 2022. With a research portfolio focused on live-cell RNA imaging, organelle-targeted imaging, and RNA-protein interaction, Dr. Peng has made significant contributions to molecular biology, including the development of genetically encoded fluorogenic aptamers and dual-color fluorescent reporting systems. Their work has been published in high-impact journals such as Analytical Chemistry, RSC Advances, Analytica Chimica Acta, and Nucleic Acids Research, amassing 73 citations across 68 documents, and an h-index of 5. Dr. Peng has led multiple research projects funded by national and provincial programs, totaling over ¥1,000,000, reflecting recognition for both scientific innovation and teaching excellence. Their studies bridge fundamental molecular genetics and practical biomedical applications, contributing to advances in gene expression analysis and targeted imaging technologies. Dr. Peng’s ongoing work continues to expand the frontiers of RNA-based molecular tools, supporting the development of next-generation diagnostic and therapeutic strategies.
Peng, Y., Li, M.Q., Gong, F.Y., Liu, X.F., Xiong, J.R., & Wang, K.R. In situ imaging of mRNA transcripts based on split-aptamer and split protein in living cells. RSC Advances, 2024, 14, 10146–10151.
Peng, Y., Shu, L.J., Deng, X.F., Huang, X., Mo, X.M., Du, F., & Tang, Z. Live-cell imaging of endogenous RNA with a genetically encoded fluorogenic allosteric aptamer. Analytical Chemistry, 2023, 95(37), 13762–13768. (CAS Q1 TOP)
Peng, Y., Ai, X.L., Yuan, Y.Y., Dong, J., Cui, X., Du, F., Huang, X., & Tang, Z. Organelle-targeted imaging based on fluorogen-activating RNA aptamers in living cells. Analytica Chimica Acta, 2022, 1209, 339816. (CAS Q1 TOP)
Peng, Y., Huang, X., Huang, T.F., Du, F., Cui, X., & Tang, Z. Combining protein and RNA quantification to evaluate promoter activity by using dual-color fluorescent reporting systems. Bioscience Reports, 2022, 41(9), BSR20211525.
Xu, Y.#, Fu, D.Q.#, Yuan, Y.#, Peng, Y., Dong, J., Du, F., Huang, X., Liu, G.X., Chen, X.H., Wang, Q.W., & Tang, Z. A heterobifunctional molecule recruits cereblon to an RNA scaffold and activates its PROTAC function. Cell Reports Physical Science, 2023, 3(10), 101064. (CAS Q2 TOP)