Abrar Mohammad Sayaf | Drugs designing | Best Researcher Award

Mr. Abrar Mohammad Sayaf | Drugs designing | Best Researcher Award

Mr. Abrar Mohammad Sayaf at Universiti Sains Malaysia, Malaysia

Author Profile

Scopus Profile
Biography of Mr. Abrar Mohammad Sayaf: A Distinguished Chemist and Researcher in Drug Design and Natural Product Synthesis 🔬🌍

Mr. Abrar Mohammad Sayaf is a highly accomplished chemist and researcher currently affiliated with the Department of Chemistry at the University of Oxford. His diverse academic and professional background spans several prestigious institutions, reflecting his profound expertise in both theoretical and applied chemistry.

Academic Background 📚

  • Ph.D. in Progress: School of Chemical Sciences, Universiti Sains Malaysia (2022-Present)
  • M.Ed. (1st Division): Alama Iqbal Open University, Islamabad, Pakistan (2016-2019)
  • B.Ed. (1st Division): Alama Iqbal Open University, Islamabad, Pakistan (2012-2014)
  • M.Sc. in Chemistry (University Distinction): University of Swat, Pakistan (2011-2013)
  • B.Sc. (1st Division): University of Malakand, Pakistan (2009-2011)

Professional Experience 🏢

  • Research Fellow: Department of Chemistry, University of Oxford (January 2024-Present)
  • Lecturer in Chemistry: University of Swat, Pakistan (2014-2020)
  • Product Development Analyst: Shaheen Pharmaceuticals, Mingora, Swat (2020-2022)
  • Director and Lecturer in Chemistry: Quantum Academia, Mingora, Swat (2012-2020)

Research Interests and Projects 🔍

  • Current Research: Prolyl Hydroxylase Domain 2 (PHD2) Inhibitors at the University of Oxford, funded by the Fundamental Research Grant Scheme (FRGS)
  • Previous Projects: Biological synthesis of Pd nanoparticles, catalysis in Suzuki cross-coupling reactions, and isolation of natural products from Delphinium roylei and Debregeasia salicifolia

Skills and Expertise 🧪

  • Computational Chemistry: Molecular docking, molecular dynamics simulation, network pharmacology, protein-protein docking, computational vaccine designing, and drug pharmacokinetics/ADMET analysis
  • Organic Synthesis: Amide synthesis, Schiff bases, carbon-carbon coupling
  • Natural Product Chemistry: Isolation and characterization
  • Analytical Techniques: Chromatography, NMR spectroscopy, IR spectroscopy, mass spectrometry, protein crystallization, and alpha screening (IC50 calculation)

Research Collaborations 🤝

  • Schofield Group, University of Oxford, England: Prolyl hydroxylase domains (PHDs) inhibition
  • Qatar University, Doha, Qatar: In silico drug discovery for infectious diseases
  • Shanghai Jiao Tong University, China: In silico drug discovery for viral diseases
  • Hunan University of Science and Technology, China: In silico drug discovery for viral diseases
  • Agri Ibrahim Cecen University, Turkey: Inhibition of carbonic anhydrases
  • University of Swat, Pakistan: In silico drug discovery for cancer treatment

Achievements and Honors 🏆

  • Research Assistance: School of Chemical Sciences, USM, Malaysia (2022-Present)
  • International Summer School Scholarship: University of A Coruña, Spain (2020)
  • University Position Holder: M.Sc. Chemistry at University of Swat (2013)
  • Various Academic Awards: Including speech competitions, talent certificates, and scholarships

📖 Publication Top Noted

Article: Molecular screening of phytocompounds targeting the interface between influenza A NS1 and TRIM25 to enhance host immune responses
  • Authors: Suleman, M., Sayaf, A.M., Khan, A., Yassine, H.M., Crovella, S.
    Journal: Journal of Infection and Public Health
    Volume: 17
    Issue: 7
    Pages: 102448
    Year: 2024
Article: Pharmacotherapeutic Potential of Natural Products to Target the SARS-CoV-2 PLpro Using Molecular Screening and Simulation Approaches
  • Authors: Sayaf, A.M., Ahmad, H., Aslam, M.A., Yeoh, K.K., Wei, D.-Q.
    Journal: Applied Biochemistry and Biotechnology
    Volume: 195
    Issue: 11
    Pages: 6959-6978
    Year: 2023
Article: Exploring the natural products chemical space through a molecular search to discover potential inhibitors that target the hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD)
  • Authors: Sayaf, A.M., Ullah Khalid, S., Hameed, J.A., Wei, D.-Q., Yeoh, K.
    Journal: Frontiers in Pharmacology
    Volume: 14
    Issue: –
    Pages: 1202128
    Year: 2023
Article: Blocking key mutated hotspot residues in the RBD of the omicron variant (B.1.1.529) with medicinal compounds to disrupt the RBD-hACE2 complex using molecular screening and simulation approaches
  • Authors: Khan, A., Randhawa, A.W., Balouch, A.R., Mohammad, A., Wei, D.-Q.
    Journal: RSC Advances
    Volume: 12
    Issue: 12
    Pages: 7318-7327
    Year: 2022
Article: Bioaccumulation of heavy metals in the tissues of Schizothorax plagiostomus at River Swat | Bioacumulação de metais pesados nos tecidos de Plagiostomo esquizotórax em River Swat
  • Authors: Shah, M., Kausar, S., Mian, J.A., Usman, K., Ahmed, D.
    Journal: Brazilian Journal of Biology
    Volume: 82
    Issue: –
    Pages: e243633
    Year: 2022
Article: An Integrated Systems Biology and Network-Based Approaches to Identify Novel Biomarkers in Breast Cancer Cell Lines Using Gene Expression Data
  • Authors: Khan, A., Rehman, Z., Hashmi, H.F., Heng, W., Wei, D.-Q.
    Journal: Interdisciplinary Sciences – Computational Life Sciences
    Volume: 12
    Issue: 2
    Pages: 155-168
    Year: 2020
Article: Immunoinformatics approaches to explore Helicobacter Pylori proteome (Virulence Factors) to design B and T cell multi-epitope subunit vaccine
  • Authors: Khan, M., Khan, S., Ali, A., Khan, A., Wei, D.-Q.
    Journal: Scientific Reports
    Volume: 9
    Issue: 1
    Pages: 13321
    Year: 2019