Mr. Manu Sharma | parasitic diseases | Best Researcher Award
Stanford University | United States
Author Profile
EARLY ACADEMIC PURSUITS
The individual embarked on an exceptional academic journey, beginning with a Bachelor of Technology and Master of Technology dual degree from the prestigious Indian Institute of Technology, New Delhi, India, in 2004. This foundational education paved the way for further specialization in molecular biology, with a PhD earned at the renowned Max Planck Institute for Infection Biology in Berlin, Germany, in 2009.
PROFESSIONAL ENDEAVORS
Currently serving as a Basic Life Research Scientist at Stanford University, California, since 2017, this scientist has contributed groundbreaking work in the regulation of gene expression in amoebae, particularly focusing on tRNA fragments. Their role as a senior member in the lab, leading independent research projects, mentoring postdoctoral fellows, and preparing impactful NIH grant proposals has solidified their leadership in the scientific community. Prior to this, they gained invaluable experience as a Postdoctoral Fellow at UCSF-Benioff Children’s Hospital in Oakland, where they made significant strides in lipid metabolism studies and contributed to commercial product development for diagnostics.
CONTRIBUTIONS AND RESEARCH FOCUS ON parasitic diseases
This scientist’s research spans the regulation of immune responses and gene expression in infectious diseases, particularly Entamoeba histolytica and Chlamydia trachomatis. Their work on extracellular vesicles, tRNA-derived fragments, and macrophage polarization is reshaping the understanding of host-parasite interactions. The innovative assays developed, such as LAMP-based diagnostics, are aiding in the advancement of multiplexed diagnostics for infectious diseases, providing a vital tool for the scientific community.
IMPACT AND INFLUENCE
The scientist’s contributions extend beyond the laboratory, influencing the academic landscape through their leadership role in the Postdoctoral Association at UCSF and service as an academic editor for PLOS One. Their work has inspired not only peer researchers but also advanced practical applications in the fields of immunology, molecular biology, and diagnostics.
ACADEMIC CITATIONS AND PUBLICATIONS
With numerous peer-reviewed publications in high-impact journals such as the Journal of Parasitology Research, MBio, and Infection and Immunity, this individual’s research has garnered global recognition. Their selected works include pivotal studies on extracellular vesicles, stress responses in protozoan parasites, and the role of tRNA-derived fragments, which have significantly advanced the field of parasitology and infectious diseases.
HONORS & AWARDS
Throughout their career, the individual has received notable accolades, including the prestigious Marie Curie Scholarship and first place in the University of Texas Southwestern Healthcare Case Competition in 2023. Their exemplary work has earned them recognition in the form of Employee Performance for Excellence in Teamwork at Evalueserve, highlighting their collaborative spirit.
LEGACY AND FUTURE CONTRIBUTIONS
Looking ahead, this scientist is poised to make further groundbreaking contributions in the fields of molecular biology, infectious disease research, and diagnostic innovations. Their work will undoubtedly continue to impact both academic and clinical practices, offering new insights into the mechanisms underlying host-parasite interactions and advancing the field of molecular diagnostics.
FINAL NOTE
This individual has demonstrated an unwavering commitment to advancing scientific knowledge and its practical application in the fight against infectious diseases. Their innovative research and leadership in the scientific community ensure that their legacy will continue to inspire future generations of researchers.
NOTABLE PUBLICATIONS
Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells
- Authors: K Rajalingam, M Sharma, C Lohmann, M Oswald, O Thieck, CJ Froelich, …
Journal: PLoS One
Year: 2008
IAP-IAP complexes required for apoptosis resistance of C. trachomatis–infected cells
- Authors: K Rajalingam, M Sharma, N Paland, R Hurwitz, O Thieck, M Oswald, …
Journal: PLoS Pathogens
Year: 2006
Apoptosis resistance in Chlamydia-infected cells: a fate worse than death?
- Authors: M Sharma, T Rudel
Journal: FEMS Immunology & Medical Microbiology
Year: 2009
HIF‐1α is involved in mediating apoptosis resistance to Chlamydia trachomatis‐infected cells
- Authors: M Sharma, N Machuy, L Böhme, K Karunakaran, AP Mäurer, TF Meyer, …
Journal: Cellular Microbiology
Year: 2011
Characterization of extracellular vesicles from Entamoeba histolytica identifies roles in intercellular communication that regulates parasite growth and development
- Authors: M Sharma, P Morgado, H Zhang, G Ehrenkaufer, D Manna, U Singh
Journal: Infection and Immunity
Year: 2020
Chlamydia trachomatis growth and development requires the activity of host Long-chain Acyl-CoA Synthetases (ACSLs)
- Authors: MA Recuero-Checa, M Sharma, C Lau, PA Watkins, CA Gaydos, D Dean
Journal: Scientific Reports
Year: 2016