Bo Zhai | Healthcare Data Analysis | Best Researcher Award

Prof Dr. Bo Zhai | Healthcare Data Analysis | Best Researcher Award

The Fourth Hospital of Harbin Medical University, China

Author Profile

Scopus

Early Academic Pursuits 📚

Dr. Bo Zhai, a highly respected Chief Physician and Associate Professor at The Fourth Hospital of Harbin Medical University, began his academic journey with a focus on hepatology and cell biology. After earning his MD, Dr. Zhai pursued advanced training as a Postdoctoral Fellow and later became a Fellow of the American College of Surgeons (FACS). His early academic work laid the foundation for his ongoing contributions to liver cancer research, particularly in the realm of hepatocellular carcinoma (HCC).

Professional Endeavors 🏥

Dr. Zhai has had a distinguished professional career, having served as a visiting scholar at the Liver Research Center of Brown University in the USA, sponsored by the National Foreign Experts Bureau. His work on liver cancer has been pivotal in understanding the complexities of HCC, a disease known for its resistance to conventional therapies like sorafenib. His international experience has broadened his research scope and enriched his academic and clinical expertise.

Contributions and Research Focus 🧬

Dr. Zhai’s primary research focus is on hepatocellular carcinoma (HCC), particularly how ASPH (Aspartate β-hydroxylase) influences cell death and contributes to chemoresistance in HCC. He has discovered that high levels of ASPH in HCC enhance proliferation, migration, and invasion, and also predict worse clinical outcomes for patients undergoing sorafenib treatment. His groundbreaking work suggests that targeting ASPH could break new ground in HCC therapy, overcoming the challenges posed by drug resistance.

Impact and Influence 🌍

Dr. Zhai’s research has had a significant impact on the field of liver cancer research, especially in understanding mechanisms of resistance to conventional cancer therapies. His studies on ASPH in HCC have opened new avenues for therapeutic interventions, providing insights into the role of autophagy, ferroptosis, and cell survival pathways in cancer progression. His work has been published in prestigious journals, including Cancer Letters, and is cited widely, underlining his contribution to the scientific community.

Academic Citations 📈

With an impressive citation index of 17.7, Dr. Zhai’s work is highly regarded in the academic community. His research publications, particularly those related to ASPH and HCC, have made substantial contributions to the understanding of liver cancer biology. His studies have provided valuable insights into the molecular mechanisms behind HCC’s resistance to chemotherapy, paving the way for new therapeutic strategies.

Technical Skills 🔬

Dr. Zhai has a wide range of technical skills, including expertise in molecular biology, cancer cell biology, and animal model studies. His proficiency in studying autophagy, ferroptosis, and tumor metastasis has made him a leader in the field of liver cancer research. Additionally, his experience with gene silencing and knockout models has allowed him to explore new potential targets for cancer treatment.

Teaching Experience 🧑‍🏫

As an Associate Professor, Dr. Zhai has contributed significantly to the education and mentoring of graduate and medical students. He has supervised numerous Master’s students and postdoctoral fellows, passing on his expertise in liver cancer research. His teaching extends beyond the classroom, as he is also involved in sharing his knowledge and findings through academic conferences and seminars.

Legacy and Future Contributions 🌱

Dr. Zhai’s legacy in liver cancer research is already well-established, with his groundbreaking work on ASPH setting the stage for future therapeutic developments. As he continues to pursue innovative approaches in HCC treatment, his research promises to lead to better clinical outcomes for patients battling liver cancer. His future contributions to the field will likely focus on developing targeted therapies that can overcome chemoresistance and improve patient survival rates.

Top Noted Publications 📖

ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma
    • Authors: Jingtao Li, Guocai Zhong, Fengli Hu, Qiushi Lin, Xiaoqun Dong, Bo Zhai
    • Journal: Cancer Letters
    • Year: 2024
Mechanisms of vascular co-option as a potential therapeutic target in hepatocellular carcinoma
    • Authors: Ming-Hao Qi, Jing-Tao Li, Bo Zhai
    • Journal: World Chinese Journal of Digestology
    • Year: 2024
Aspartate-β-hydroxylase as a promising prognostic and therapeutic biomarker for HBV-positive hepatocellular carcinoma
    • Authors: Jingtao Li, Zongwen Wang, Xiaohang Ren, WenYu Liu, Shicong Zeng, Bo Zhai
    • Journal: Research Square
    • Year: 2023
Is hepatic resection always a better choice than radiofrequency ablation for solitary hepatocellular carcinoma regardless of age and tumor size?
    • Authors: Shicong Zeng, Yao Zhang, Zongwen Wang, Qiankun Zhu, Yan Yan, Bo Zhai
    • Journal: Biomolecules & Biomedicine
    • Year: 2023
Identification of risk and prognostic factors for intrahepatic vascular invasion in patients with hepatocellular carcinoma: a population-based study
    • Authors: Shicong Zeng, Zongwen Wang, Qiankun Zhu, Fengli Hu, Lishan Xu, Bo Zhai
    • Journal: Translational Cancer Research
    • Year: 2022

Hao Gao | Healthcare Data Analysis | Best Researcher Award

Prof. Hao Gao | Healthcare Data Analysis | Best Researcher Award

Jinan University, China

Author Profiles

orcid

Scopus

Research Gate

👨‍🎓 Early Academic Pursuits

Prof. Hao Gao began his academic journey with a strong foundation in natural medicine chemistry. He received his PhD from Shenyang Pharmaceutical University in 2005, focusing on the chemistry of natural medicines. This early academic work set the stage for his future contributions to the field of Traditional Chinese Medicine (TCM). After completing his doctorate, he further honed his expertise through postdoctoral training at Tsinghua University (2006-2008), a renowned institution that significantly influenced his approach to scientific research and innovation.

💼 Professional Endeavors and Leadership

Prof. Gao’s professional trajectory has been marked by leadership roles that have shaped his career and the direction of his research. In 2008, he joined the Institute of Traditional Chinese Medicine & Natural Products at Jinan University as a faculty member. Since 2013, he has been a professor at the university and, in 2016, assumed the position of Head of the Institute of Traditional Chinese Medicine & Natural Products. In 2020, he expanded his administrative responsibilities by taking on the role of Director of the Science and Technology Department at Jinan University. Prof. Gao’s leadership has been pivotal in fostering multidisciplinary collaborations and advancing research initiatives in natural medicine chemistry.

🔬 Contributions and Research Focus

Prof. Gao’s research is primarily centered on natural medicine chemistry, with a particular focus on the active compounds and technological advancements related to Traditional Chinese Medicine (TCM). His work is dedicated to exploring under-researched medicinal materials like Lycium barbarum, Angelica sinensis, and Ophiocordyceps sinensis, which are central to TCM practices. Prof. Gao has made significant strides in identifying bioactive substances and developing novel drugs derived from TCM. Notably, his research has led to the discovery of four classes of lead compounds for anti-dementia drugs, all characterized by independent intellectual property rights.

🌍 Impact and Influence

Prof. Gao’s impact extends beyond academia, with substantial contributions to the modernization of TCM and drug development. His collaborations with international experts, such as Professor Ikuro Abe from the University of Tokyo, have facilitated the establishment of the International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development, a joint initiative between China’s Ministry of Education and Jinan University. This partnership exemplifies Prof. Gao’s influence on global TCM research and highlights his role in pushing the boundaries of natural product-based drug development.

📚 Academic Citations and Recognition

Prof. Gao’s research has gained widespread recognition, reflected in his 4100 citations across various SCI journals. His work has significantly contributed to the advancement of natural medicine chemistry and TCM, making him a highly influential figure in the field. His numerous publications, with 195 journal articles and one book published, continue to shape research in TCM and pharmacology. Moreover, his leadership as an editor for the China Section of the Journal of Natural Medicines and as an editorial board member for Acta Pharmaceutica Sinica B highlights his prominence in the academic community.

🛠️ Technical Skills and Innovations

Prof. Gao’s technical expertise spans various critical areas, including the extraction, isolation, and characterization of bioactive compounds from TCM. His innovations in pharmacodynamic constituents of TCM have contributed to the discovery of novel drug candidates, some of which are in the process of patenting. With over 71 patents published or pending, Prof. Gao stands at the forefront of translating TCM practices into scientifically validated therapeutic solutions. His lab continues to focus on critical technologies that aim to enhance the efficacy and safety of TCM-derived medicines.

👩‍🏫 Teaching Experience

In addition to his research, Prof. Gao has been an integral part of the academic community at Jinan University, mentoring and guiding students in the fields of pharmacology and natural medicine chemistry. His teaching philosophy integrates cutting-edge research with practical applications in TCM, ensuring that his students are well-equipped to pursue careers in both academia and industry. As a mentor, Prof. Gao has inspired numerous graduate students and postdoctoral researchers, many of whom have gone on to make their own contributions to TCM and drug development.

🌱 Legacy and Future Contributions

Prof. Gao’s legacy is built on his pioneering work in natural medicine chemistry and the modernization of Traditional Chinese Medicine. His research continues to influence the field, with ongoing projects that promise to uncover more bioactive compounds and therapeutic agents. As his career progresses, Prof. Gao remains committed to advancing TCM through innovation and interdisciplinary collaboration. His future work will likely expand the global recognition of TCM-based drugs, pushing the boundaries of natural product drug discovery and pharmacology for the betterment of human health.

🌟 Professional Memberships and Editorial Roles

Prof. Gao is an active member of the China Association of Chinese Medicine, where he serves as Vice Chairperson of the Youth Work Committee. His role in professional societies and editorial boards, including his editorial positions in high-impact journals, underscores his authority in the fields of natural products and biosynthesis. His leadership extends to guiding the next generation of researchers and practitioners in these fields.

📖 Top Noted Publications 

Functional and structural dissection of glycosyltransferases underlying the glycodiversity of wolfberry-derived bioactive ingredients lycibarbarspermidines
    • Authors: Li, S.-Y., Wang, G.-Q., Long, L., Abe, I., Gao, H.
    • Journal: Nature Communications
    • Year: 2024
Identification of three novel P450 enzymes involved in the oxidative modification of a newly discovered fusicoccane diterpene
    • Authors: Dong, L., Liu, J.-Y., Wang, G.-Q., Hu, D., Gao, H.
    • Journal: Bioorganic Chemistry
    • Year: 2024
Targeted Discovery of a Natural ortho-Quinone Methide Precursor and Green Generation of Its Oligomers
    • Authors: Wang, X.-X., Deng, B.-Q., Ouyang, Z.-Q., Yao, X.-S., Gao, H.
    • Journal: Journal of Natural Products
    • Year: 2024
A Functional Switch Between Asperfumene and Fusicoccadiene Synthase and Entrance to Asperfumene Biosynthesis through a Vicinal Deprotonation-Reprotonation Process
    • Authors: Liu, J.-Y., Lin, F.-L., Taizoumbe, K.A., Gao, H., Dickschat, J.S.
    • Journal: Angewandte Chemie – International Edition
    • Year: 2024
Mechanistic characterisation of a fungal fusicoccane-type diterpene synthase involved in the biosynthesis of talaro-7,13-diene
    • Authors: Lin, F.-L., Taizoumbe, K.A., Wang, Y.-X., Gao, H., Dickschat, J.S.
    • Journal: Organic and Biomolecular Chemistry
    • Year: 2024

Wei Liang | Healthcare Data Analysis | Best Researcher Award

Dr. Wei Liang | Healthcare Data Analysis | Best Researcher Award

Doctorate at East China University of Science and Technology, China

 Author Profile 👨‍🎓

Early Academic Pursuits 🎓

Dr. Wei Liang embarked on his academic journey at East China University of Science and Technology, where he earned his Bachelor’s degree in Engineering (B.E.) in 2020. His interest in Brain-Computer Interfaces (BCI) and Machine Learning became evident during his undergraduate studies, setting the stage for his continued academic success. Currently, he is pursuing his PhD at the same institution, delving deeper into the intersection of neuroscience, computer science, and biomedical engineering. His early education laid a strong foundation for his research in the emerging field of BCI technology.

Professional Endeavors 💼

As a PhD candidate, Wei Liang is already contributing to the rapidly evolving field of Brain-Computer Interfaces, particularly in motor imagery and neural signal processing. His research involves collaboration with prominent experts in the fields of computer science, neuroscience, and biomedical engineering, such as Andrzej Cichocki, Ian Daly, and Brendan Allison. Liang’s professional journey has been shaped by these collaborations, allowing him to gain insights from diverse disciplines, further honing his expertise in BCI.

Contributions and Research Focus 🧠

Wei Liang’s research focuses on advancing Brain-Computer Interface (BCI) technology, particularly in motor imagery and neural signal processing. His work has led to the development of SecNet, a second-order neural network designed to improve motor imagery decoding from electroencephalography (EEG) signals. Liang’s innovative approaches include variance-preserving spatial patterns for EEG signal processing and the use of graph convolutional networks for optimal channel selection. These contributions have enhanced the accuracy and reliability of BCI systems, making them more applicable to real-world scenarios such as stroke rehabilitation and neural engineering.

Impact and Influence 🌍

Wei Liang’s work is making significant strides in improving BCI systems, which have far-reaching applications in medicine, rehabilitation, and human-computer interaction. By optimizing EEG decoding strategies, his research could impact the development of more effective neuroprosthetics and assistive technologies for individuals with motor impairments. His collaboration with leading researchers from around the world further amplifies the global impact of his work, positioning him as a rising star in BCI research.

Academic Citations 📚

Despite being in the early stages of his career, Wei Liang has already made a notable impact on the academic community. His research has led to the publication of five papers, accumulating a total of 14 citations and an h-index of 2. Notable papers include works published in Information Processing & Management, Frontiers in Human Neuroscience, and IEEE Journal of Biomedical and Health Informatics, among others. These publications highlight his contributions to improving BCI systems and their applications.

Technical Skills 🛠️

Wei Liang possesses a strong technical skill set, particularly in the areas of machine learning, neural network architecture, and EEG signal processing. He has expertise in developing novel algorithms for motor imagery decoding, including the use of second-order neural networks and graph convolutional networks. Liang is proficient in various computational tools and programming languages necessary for his research, positioning him as an expert in his field.

Teaching Experience 🏫

Though primarily focused on research, Wei Liang’s academic journey has also included some teaching experience, collaborating with faculty and providing guidance to students. His strong academic background, coupled with his research expertise, allows him to mentor and inspire others in the field of Brain-Computer Interfaces.

Legacy and Future Contributions 🌟

Wei Liang’s research trajectory holds great promise for shaping the future of Brain-Computer Interface technology. His innovative methodologies have the potential to revolutionize how we understand and utilize EEG signals for communication and rehabilitation. In the long term, his contributions could lead to breakthroughs in neuroprosthetics, enhancing the quality of life for individuals with disabilities. With continued dedication and innovation, Liang is on track to leave a lasting legacy in the realm of neuroscience and technology.

Teaching and Mentorship 🧑‍🏫

Although Liang is primarily focused on research, his experiences collaborating with top researchers and participating in academia have enriched his teaching and mentorship skills. His ability to translate complex ideas into understandable concepts makes him an effective communicator, ready to guide the next generation of researchers in the field of BCI.

Awards and Recognition 🏆

Wei Liang has been recognized for his groundbreaking research, publishing in high-impact journals and earning accolades for his contributions to BCI technology. As a promising young researcher, he is poised to receive even greater recognition as his work continues to influence and shape the future of the field.

Top Noted Publications📖

Novel Channel Selection Model Based on Graph Convolutional Network for Motor Imagery
    • Authors: W Liang, J Jin, I Daly, H Sun, X Wang, A Cichocki
    • Journal: Cognitive Neurodynamics
    • Year: 2023
Variance Characteristic Preserving Common Spatial Pattern for Motor Imagery BCI
    • Authors: W Liang, J Jin, R Xu, X Wang, A Cichocki
    • Journal: Frontiers in Human Neuroscience
    • Year: 2023
SecNet: A Second Order Neural Network for MI-EEG
    • Authors: W Liang, BZ Allison, R Xu, X He, X Wang, A Cichocki, J Jin
    • Journal: Information Processing & Management
    • Year: 2025
Multiscale Spatial-Temporal Feature Fusion Neural Network for Motor Imagery Brain-Computer Interfaces
    • Authors: J Jin, W Chen, R Xu, W Liang, X Wu, X He, X Wang, A Cichocki
    • Journal: IEEE Journal of Biomedical and Health Informatics
    • Year: 2024
Leveraging Transfer Superposition Theory for StableState Visual Evoked Potential Cross-Subject Frequency Recognition
    • Authors: X He, BZ Allison, K Qin, W Liang, X Wang, A Cichocki, J Jin
    • Journal: IEEE Transactions on Biomedical Engineering
    • Year: 2024