Lishu Guo | Insight Interlace | Best Researcher Award

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Assoc Prof Dr. Lishu Guo | Insight Interlace | Best Researcher Award

Assoc Prof Dr. Lishu Guo at Columbia University, China

👨‍🎓 Profiles

 📚 Academic Background 

Lishu Guo is an accomplished Associate Research Scientist at Columbia University, New York, specializing in mitochondrial bioenergetics and metabolic reprogramming. With a global academic and research background, Dr. Guo has contributed significantly to understanding mitochondrial dynamics and their implications in cancer and metabolic disorders.

🎓 Education

Dr. Guo earned a Ph.D. in Biomedical Science from the University of Padova, Italy, focusing on mitochondrial permeability transition and F-ATP synthase (2015-2018). She also holds a Master’s in Pharmacology from Lanzhou University, China (2012-2014), and a Bachelor’s in Medicine from Henan University, China (2008-2012).

đź’Ľ Professional Experience

Dr. Guo is currently serving as an Associate Research Scientist at Columbia University’s Department of Anesthesiology (since August 2024). Previously, she worked as a Young Associate Researcher at the Greater Bay Area Institute of Precision Medicine, Fudan University, China (2022-2024) and as an Assistant Researcher at Tongji University’s School of Medicine, China (2019-2022). She also completed a Fellowship at the University of Padova (2018-2019) and started her career as an Assistant Researcher at Shanghai Haohai Biological Technology Co., Ltd. (2014-2015).

🔬 Research Interests

Dr. Guo’s research interests include mitochondrial channels and permeability transition, oxidative phosphorylation, F-ATP synthase dynamics, oxidative stress, calcium homeostasis, and metabolic reprogramming. She explores these areas to understand their roles in cellular function and disease mechanisms.

🏆 Awards and Funding 

Dr. Guo has received funding from the Shanghai Sailing Program (2020-2023) and the Shanghai Tenth People’s Hospital (2021-2023).

🤝 Memberships 

Dr. Guo is a member of the Shanghai Overseas Returned Scholars Association and the Guangzhou Overseas Returned Scholars Association.

📝 Reviewer 

Dr. Guo serves as a reviewer for several journals, including ACS Chemical Neuroscience, Biochemical Pharmacology, and Mitochondrial Communications.

💡Patents 

Dr. Guo holds patents for MTCH2 in cancer treatment drugs related to iron death (2023) and a composition for enhancing immune function (2023).

đź“– Publications

Title: F-ATP synthase inhibitory factor 1 regulates metabolic reprogramming involving its interaction with c-Myc and PGC1α
  • Author(s): Guo, L., Gu, Z.
  • Journal: Frontiers in Oncology
  • Year: 2023
Title: Mitochondrial ATP synthase inhibitory factor 1 interacts with the p53–cyclophilin D complex and promotes opening of the permeability transition pore
  • Author(s): Guo, L.
  • Journal: Journal of Biological Chemistry
  • Year: 2022
Title: Mitochondria and the permeability transition pore in cancer metabolic reprogramming
  • Author(s): Guo, L.
  • Journal: Biochemical Pharmacology
  • Year: 2021
Title: Arg-8 of yeast subunit e contributes to the stability of F-ATP synthase dimers and to the generation of the full-conductance mitochondrial megachannel
  • Author(s): Guo, L., Carraro, M., Carrer, A., Bernardi, P., Lippe, G.
  • Journal: Journal of Biological Chemistry
  • Year: 2019
Title: Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal
  • Author(s): Guo, L., Carraro, M., Sartori, G., Petronilli, V., Bernardi, P.
  • Journal: Journal of Biological Chemistry
  • Year: 2018