zhongyuan xiang | laboratory medicine | Best Researcher Award

Prof. zhongyuan xiang | laboratory medicine | Best Researcher Award

the second Xiangya Hospital of Central South University | China

Author Profile

Scopus

๐Ÿ“ Summary

Zhongyuan Xiang, a dedicated and experienced medical professional, is the Secretary and Director of the Department of Laboratory Medicine at Xiangya Second Hospital, Central South University. He is an expert in medical diagnostics and laboratory technologies with over a decade of experience. He is deeply involved in research on autoimmune diseases, artificial intelligence in diagnostics, and cancer biomarkers.

๐ŸŽ“ Education

  • Ph.D. in Medical Sciences
  • Master’s Supervisor at Central South University, guiding graduate students in the field of medical testing.

๐Ÿ’ผ Professional Experience

  • Secretary & Director, Department of Laboratory Medicine, Xiangya Second Hospital, Central South University.
  • Senior Technician, Chief Medical Scientist, with extensive contributions to the development of clinical testing techniques and laboratory management.

๐Ÿ“š Academic Positions

  • Committee Member, Chinese Medical Association Biochemistry Group
  • Committee Member, Chinese Stroke Society Clinical Laboratory Branch
  • Committee Member, Chinese Medical Device Industry Association POCT Branch
  • Various leadership roles in regional medical societies in Hunan Province.

๐Ÿง‘โ€๐Ÿ”ฌ Research Interests On laboratory medicine

Zhongyuan’s research spans the molecular mechanisms of autoimmune diseases (e.g., Systemic Lupus Erythematosus), clinical diagnostics innovations (such as AI in laboratory testing), and cancer detection techniques, including high throughput genetic and biochemical diagnostics.

โš™๏ธ Technical Skills

  • Advanced skills in laboratory diagnostics, including molecular biology techniques, immunology, and AI-driven diagnostics tools.
  • Expert in high throughput testing and clinical laboratory systems.
  • In-depth knowledge of biochemical analysis, clinical trials, and diagnostic kit development.

๐Ÿง‘โ€๐Ÿซ Teaching Experience

  • Masterโ€™s thesis supervisor for graduate students in clinical laboratory sciences at Central South University.
  • Course leader for emergency response training in clinical diagnostics.
  • Regular contributor to textbooks and educational resources for medical professionals.

๐Ÿ”ฌ Research Contributions

  • Funded Research Projects: Lead multiple nationally funded research projects, focusing on autoimmune disease mechanisms and the clinical application of automated diagnostic systems.
  • Publications: Over 30 publications in high-impact journals, with notable work on diagnostic biomarkers and clinical diagnostic technologies.

๐Ÿ† Honors & Awards

  • First Place, Hunan Province Science and Technology Progress Award (2024)
  • Hunan Province Graduate Student Excellence Award (2022)
  • Second Place, Hunan Province Science and Technology Progress Award
  • Third Place, Clinical Medical Technology Achievement Award, Xiangya Second Hospital, Central South University

๐Ÿ’ก Patents

  • Practical New Utility Patent: “A Multifunctional Indicator Operation Card” (March 2022).

๐Ÿ“‘ย  Notable Publicationsย ย 

Dual genes manipulation enhanced chemotherapy potentiates antitumor immunity based on extracellular vesicle system for glioblastoma treatment
  • ๐Ÿ“‘ Authors: Y. Yang, X. Wang, M. Wang, J. Chen, Y. Duo
    ๐Ÿ“ฐ Journal: Chemical Engineering Journal
    ๐Ÿ“… Year: 2024
Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine
  • ๐Ÿ“‘ Authors: Y. Duo, L. Han, Y. Yang, G. Luo, B. Tang
    ๐Ÿ“ฐ Journal: Chemical Reviews
    ๐Ÿ“… Year: 2024
D1-like dopamine receptors promote B-cell differentiation in systemic lupus erythematosus
  • ๐Ÿ“‘ Authors: Z. Xiang, F. Wu, Z. He, W. Liu, M. Yang
    ๐Ÿ“ฐ Journal: Cell Communication and Signaling
    ๐Ÿ“… Year: 2024

Laurence Vaughan | Medical Diagnostics | Best Researcher Award

Dr. Laurence Vaughan | Medical Diagnostics | Best Researcher Award

Dr. Laurence Vaughan at Becton Dickinson and Company, United States

๐Ÿ‘จโ€๐ŸŽ“ Professional Profile

๐ŸŽ“ Early Academic Pursuits

Dr. Laurence Vaughan began his academic journey at the University of Dublin, Trinity College, where he earned a BA (Honors) in Natural Sciences (Genetics) in 1986, followed by a Ph.D. in Molecular Microbiology in 1991. His doctoral research focused on the aroA gene of Aeromonas salmonicida, contributing to foundational knowledge in microbiology and vaccine development.

๐Ÿข Professional Endeavors

Dr. Vaughanโ€™s career spans over three decades in the biotechnology and molecular diagnostics sectors. Currently, he serves as the Director of Scientific Affairs at Becton Dickinson and Company, focusing on integrated diagnostic solutions for womenโ€™s health, particularly cervical cancer screening. His past roles include R&D leadership at QIAGEN and Corning Incorporated, where he made significant advancements in molecular assay development and product support.

๐ŸŒŸ Contributions and Research Focus

Dr. Vaughan has led teams in developing groundbreaking products such as the BD Onclarity cervical cancer screening test, which received CE Mark approval in 2014 and US-PMA approval in 2018. He has authored content for international conferences and peer-reviewed publications, emphasizing his commitment to advancing scientific knowledge and product innovation in the diagnostics field.

๐ŸŒ Impact and Influence

His work has not only shaped diagnostic guidelines but has also influenced industry standards, as seen with the American Society for Colposcopy and Cervical Pathology (ASCCP) management guidelines launched in 2020. Dr. Vaughan’s expertise is recognized internationally, making him a sought-after speaker at various conferences.

๐Ÿ“š Academic Cites

Dr. Vaughan has made notable contributions to the field of vaccinology, evidenced by multiple patents and publications. His editorial experience as the Editor-in-Chief of “Diseases of Aquatic Organisms” from 1995 to 1999 further underscores his leadership in academic discourse.

๐Ÿ”ง Technical Skills

Dr. Vaughan possesses extensive technical skills in molecular biology, microbiology, and genetics. His proficiency in managing clinical trials, particularly in the R&D lead for Onclarity HPV clinical trials, highlights his ability to oversee complex scientific projects.

๐Ÿ‘ฉโ€๐Ÿซ Teaching Experience

Throughout his career, Dr. Vaughan has demonstrated a passion for education and mentorship. He has developed and delivered training for global customers and internal teams, showcasing his strong communication and interpersonal skills.

๐Ÿ… Legacy and Future Contributions

Dr. Vaughan’s legacy includes a robust portfolio of innovations and leadership in the biotech field. His achievements, such as the Becton Dickinson Wesley J. Howe Award for Technological Innovation in 2013, reflect his dedication to advancing science and technology. Looking ahead, he aims to continue contributing to the development of effective diagnostic solutions and vaccines, focusing on emerging health challenges.

 

๐Ÿ“– Top Noted Publications

Variables that impact HPV test accuracy during vaginal self collection workflow for cervical cancer screening

Authors: Vaughan, L., Gary, D., Shah, M., Galbraith, L., Parvu, V.
Journal: Gynecologic Oncology Reports
Year: 2024

Risk stratification of HPV-positive results using extended genotyping and cytology: Data from the baseline phase of the Onclarity trial

Authors: Stoler, M.H., Parvu, V., Yanson, K., Andrews, J., Vaughan, L.
Journal: Gynecologic Oncology
Year: 2023

Validation of a New High-Throughput BD COR System Using the BD CTGCTV2 Assay

Authors: Taylor, S., Rucki, A., Lockamy, E., Vaughan, L., Greene, W.
Journal: Journal of Molecular Diagnostics
Year: 2022

Evaluation of the Onclarity HPV assay on the high-throughput COR system

Authors: Taylor, S.N., Eckert, K., Rucki, A.A., Vaughan, L.M., Greene, W.H.
Journal: Expert Review of Molecular Diagnostics
Year: 2021

Cotesting in cervical cancer screening

Authors: Malinowski, D.P., Broache, M., Vaughan, L., Andrews, J., Gary, D.
Journal: American Journal of Clinical Pathology
Year: 2021

Analytical and clinical sample performance characteristics of the onclarity assay for the detection of human papillomavirus

Authors: Young, S., Vaughan, L., Yanson, K., Cooper, C.K., van der Pol, B.
Journal: Journal of Clinical Microbiology
Year: 2021