Naiwei Lu | Data Analysis | Best Researcher Award

Assoc Prof Dr. Naiwei Lu | Data Analysis | Best Researcher Award

Changsha University of Science of Technology, China

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đŸ‘šâ€đŸ« Associate Prof. Dr. Naiwei Lu

Assoc. Prof. Dr. Naiwei Lu is an Associate Professor in Civil Engineering at Changsha University of Science and Technology (CSUST), China. His research primarily focuses on reliability and safety in bridge engineering. He has a strong background in system reliability evaluation, fatigue analysis, and structural health monitoring, which he applies to the engineering and maintenance of long-span bridges. Dr. Lu is an active member of various international research communities and has been involved in multiple national and international projects.

🎓 Education Background

Dr. Naiwei Lu earned his Ph.D. in Civil Engineering from Changsha University of Science and Technology (CSUST) in 2015, under the supervision of Prof. Yang Liu. Prior to that, he completed his Master’s degree in Civil Engineering in 2011 and his Bachelor’s degree in Bridge Engineering in 2008, all at CSUST, Changsha, China. His academic journey laid a strong foundation for his expertise in bridge engineering and reliability analysis.

đŸ’Œ Employment and Research Experience

Dr. Lu’s academic career began in 2015 when he became a Postdoctoral Researcher at Southeast University in Nanjing, China, where he worked under Prof. Mohammad Noori. He also held a Postdoctoral Researcher position at Leibniz University Hannover, Germany, working with Prof. Michael Beer. Since 2020, Dr. Lu has been serving as an Associate Professor at CSUST, where he also previously worked as a Lecturer from 2017 to 2019. His diverse academic and international experiences contribute to his deep expertise in bridge engineering.

💰 Research Funding

Dr. Lu has been the Principal Investigator (PI) of several funded research projects, including the National Science Funding in China for research on structural health monitoring of suspension bridges and the fatigue reliability evaluation of steel bridge decks. He has received significant funding support for his work in system reliability and dynamic analysis, with total funding exceeding „1 million for his various research initiatives. These projects aim to develop advanced methods for assessing the reliability and safety of long-span bridges.

🔍 Research Interests

Dr. Lu’s research spans several cutting-edge topics in structural engineering. His main research interests include system reliability evaluation of long-span bridges using intelligent algorithms đŸ€–, fatigue reliability of stay cables and orthotropic steel bridge decks 🌉, and probabilistic modeling using data from structural health monitoring 📊. He is also focused on intelligent maintenance and management of in-service bridges ⚙, as well as uncertainty quantification in structural engineering đŸ› ïž.

📚 Teaching Experience

As an educator, Dr. Lu teaches undergraduate courses such as Principle of Structural Design (in both Chinese and English) and Building Information Modeling (BIM) Technology (in Chinese). He has supervised 24 undergraduate students and 4 postgraduate students between 2017 and 2020, guiding them in various aspects of civil engineering, particularly related to bridge design, maintenance, and reliability.

đŸ—ïž Engineering Activities

In addition to his academic role, Dr. Lu is a Registered Construction Engineer and a Registered Inspection Engineer in Municipal Engineering and Bridge & Tunnel Engineering, respectively. His engineering activities include overseeing the structural safety of long-span bridges during construction đŸ—ïž, conducting structural health monitoring of suspension bridges 🌉, and contributing to the detection and reinforcement of aging bridges đŸ› ïž. He has also been involved in the advance geological forecasting and monitoring of tunnels during construction, working on over five extra-long tunnels.

Dr. Naiwei Lu’s work integrates advanced intelligent algorithms, data-driven methods, and structural health monitoring to enhance the safety, reliability, and longevity of bridges and infrastructure systems. His research and engineering expertise continue to make significant contributions to the field of civil engineering.

📖Top Noted Publications 

Structural damage diagnosis of a cable-stayed bridge based on VGG-19 networks and Markov transition field: numerical and experimental study

Authors: Naiwei Lu, Zengyifan Liu, Jian Cui, Lian Hu, Xiangyuan Xiao, Yiru Liu

Journal: Smart Materials and Structures

Year: 2025

Coupling effect of cracks and pore defects on fatigue performance of U-rib welds

Authors: Yuan Luo, Xiaofan Liu, Fanghuai Chen, Haiping Zhang, Xinhui Xiao, Naiwei Lu

Journal: Structures

Year: 2025

A Time–Frequency-Based Data-Driven Approach for Structural Damage Identification and Its Application to a Cable-Stayed Bridge Specimen

Authors: Naiwei Lu, Yiru Liu, Jian Cui, Xiangyuan Xiao, Yuan Luo, Mohammad Noori

Journal: Sensors

Year: 2024

A Novel Method of Bridge Deflection Prediction Using Probabilistic Deep Learning and Measured Data

Authors: Xinhui Xiao, Zepeng Wang, Haiping Zhang, Yuan Luo, Fanghuai Chen, Yang Deng, Naiwei Lu, Ying Chen

Journal: Sensors

Year: 2024

Experimental and numerical investigation on penetrating cracks growth of rib-to-deck welded connections in orthotropic steel bridge decks

Authors: Zitong Wang, Jun He, Naiwei Lu, Yang Liu, Xinfeng Yin, Haohui Xin

Journal: Structures

Year: 2024

Fatigue Reliability Assessment for Orthotropic Steel Decks: Considering Multicrack Coupling Effects

Authors: Jing Liu, Yang Liu, Guodong Wang, Naiwei Lu, Jian Cui, Honghao Wang

Journal: Metals

Year: 2024

Xibing Xu | Data Science | Best Researcher Award

Dr. Xibing Xu | Data Science | Best Researcher Award

Shenzhen Medical Academy of Research and Translation, China

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Early Academic Pursuits 🎓

Dr. Xibing Xu’s academic journey began with a solid foundation in biological sciences, leading to his Master’s degree from Shandong University in 2012. His Master’s thesis focused on the two-component signal transduction systems of Streptomyces hygroscopicus. This foundational research sparked his interest in bacterial biology and set the stage for his doctoral studies at Sichuan University. Dr. Xu’s Ph.D. thesis, completed in 2015, centered on “Protein homeostasis regulation and ubiquitin-like systems in bacteria,” deepening his expertise in bacterial systems and protein regulation.

Professional Endeavors đŸ’Œ

his Ph.D., Dr. Xu expanded his research horizons by embarking on various international and prestigious roles. In 2017-2018, he was awarded a visiting scholarship by the China Scholarship Council, enabling him to work as a visiting scholar at the Laboratoire de Microbiologie et Génétique Moléculaire (LMGM) in Toulouse, France. This experience enhanced his research capabilities and fostered a deeper understanding of bacterial molecular mechanisms. From 2020 to the present, Dr. Xu has served as a Postdoctoral Fellow at LMGM, where he leads the ANR project M-Tox, which investigates translational control by HigB1 and MenT toxins in Mycobacterium tuberculosis.

Contributions and Research Focus 🔬

Dr. Xu’s research is at the cutting edge of microbiology, focusing on bacterial growth inhibition mechanisms mediated by toxins in toxin-antitoxin systems. Specifically, his work on deleterious tRNA nucleotidyltransferase toxins, like MenT in Mycobacterium tuberculosis, has unveiled novel bacterial mechanisms that regulate translation and protein homeostasis. His research involves exploring the role of tRNA biology in bacterial growth control and the interaction between tRNA and toxin proteins, a focus that has the potential to inform future therapeutic strategies for bacterial infections. His expertise extends to RNA-seq, enzymology, and protein-RNA/DNA interactions, all of which contribute to a deeper understanding of bacterial survival and virulence.

Impact and Influence 🌍

Dr. Xu’s work has far-reaching implications in microbial Microbiologie and therapeutic development. By identifying key mechanisms that control bacterial growth through toxin-antitoxin systems, his research addresses critical challenges in combating drug-resistant bacterial infections. His investigations into tRNA biology have provided insights into how bacteria regulate protein synthesis, which could lead to the development of novel antimicrobial strategies. His innovative research has garnered attention within the scientific community, reflected in invitations to present at major international conferences such as the 29th International tRNA Conference in 2024.

Academic Citations 📚

Dr. Xu’s contributions to the field have not only enhanced scientific knowledge but have also been widely recognized and cited in academic publications. His work on toxin-antitoxin systems and tRNA nucleotidyltransferase toxins has attracted significant attention in the microbiology and biochemistry fields. As his research continues to influence studies on bacterial translation control, his citation index is expected to grow, cementing his reputation as an expert in bacterial growth regulation and antibiotic resistance mechanisms.

Technical Skills đŸ› ïž

Dr. Xu possesses a broad array of technical skills in biochemistry and molecular biology, enabling him to conduct complex experimental research. He is proficient in RNA-seq library design and construction, protein-DNA/RNA interaction analysis, and toxin protein purification and activity assays. Additionally, he has extensive experience in cell-free transcription and translation assays, essential for studying the mechanistic details of translation regulation in bacteria. His technical prowess underpins the success of his innovative research in bacterial biology and protein homeostasis.

Teaching Experience đŸ‘šâ€đŸ«

Dr. Xu has a strong track record in teaching and academic supervision. From 2015 to 2020, he taught various courses such as Medical Biology, Medical Genetics, and Medical Cell Biology at Henan University of Science and Technology. His teaching not only involved extensive classroom hours but also practical experimental courses, allowing students to gain hands-on experience in molecular biology techniques. Since 2024, Dr. Xu has been supervising Master’s students at the University Paul Sabatier in Toulouse, mentoring students on projects related to phage peptides and protein homeostasis in bacteria, ensuring the next generation of scientists is equipped with the necessary research skills.

Legacy and Future Contributions 🌟

Dr. Xu’s current and future research promises to continue his legacy of groundbreaking work in microbiology, particularly in the areas of bacterial toxin-antitoxin systems and translation control. As a postdoctoral fellow and researcher at LMGM, he is leading projects that could revolutionize our understanding of bacterial growth regulation, with direct applications in combating drug-resistant Mycobacterium tuberculosis. His ongoing research, mentorship, and commitment to expanding scientific knowledge will ensure that his contributions to the field of microbiology will continue to grow in impact and influence.

 Top Noted Publications 📖

Title: Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Authors: Tom J. Arrowsmith, Xibing Xu, Shangze, Ben Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, Pierre Genevaux, Tim R. Blower
Journal: Nature Communications
Year: 2024

Title: MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding

Authors: Xibing Xu, Ben Usher, C. Gutierrez, R. Barriot, T.J. Arrowsmith, X. Han, P. Redder, O. Neyrolles, T.R. Blower, P. Genevaux
Journal: Nature Communications
Year: 2023

Title: Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis

Authors: MoĂŻse, Emmanuel Giudice, Xibing Xu, Hatice Akarsu, Patricia Bordes, ValĂ©rie Guillet, Donna-Joe Bigot, Nawel Slama, Gaetano D’Urso, Sophie Chat et al.
Journal: Nature Communications
Year: 2022

Title: ClpXP-mediated Degradation of the TAC Antitoxin is Neutralized by the SecB-like Chaperone in Mycobacterium tuberculosis

Authors: Pauline Texier, Patricia Bordes, Jyotsna Nagpal, Ambre Julie Sala, Moise Mansour, Anne-Marie Cirinesi, Xibing Xu, David Andrew Dougan, Pierre Genevaux
Journal: Journal of Molecular Biology
Year: 2021

Title: The ubiquitin-like modification by ThiS and ThiF in Escherichia coli

Authors: Xibing Xu, Tao Wang, Yulong Niu, Ke Liang, Yi Yang
Journal: International Journal of Biological Macromolecules
Year: 2019

Title: BAH1 an E3 Ligase from Arabidopsis thaliana Stabilizes Heat Shock Factor σ32 of Escherichia coli by Interacting with DnaK/DnaJ Chaperone Team

Authors: Xibing Xu, Ke Liang, Yulong Niu, Yan Shen, Xuedong Wan, Haiyan Li, Yi Yang
Journal: Current Microbiology
Year: 2018