Hermona Soreq – molecular neuroscience – Outstanding Scientist Award

Early Academic Pursuits

Prof. Hermona Soreq's academic journey began with a solid foundation in biochemistry and microbiology at The Hebrew University of Jerusalem, where she earned her Bachelor of Science in 1967. She further pursued her Master’s degree at Tel Aviv University, focusing on biochemistry and chemistry teaching, which she completed in 1970. Her academic rigor and passion for molecular studies led her to The Weizmann Institute of Science, where she obtained her PhD in Biochemistry in 1976. Soreq's early career was marked by a prestigious Fogarty Fellowship at Rockefeller University, allowing her to delve into molecular cell biology from 1977 to 1979.

Professional Endeavors

Prof. Hermona Soreq's professional career is distinguished by her long-term association with The Hebrew University of Jerusalem. She joined the faculty in 1986 as the Slesinger Chair of Molecular Neuroscience, a position she has held with distinction. Her roles have included serving as the elected Dean of the Faculty of Mathematics and Natural Sciences from 2005 to 2008, and she is a founding member of the Edmond and Lily Safra Center for Brain Sciences (ELSC). Additionally, Soreq has held prominent positions at the Weizmann Institute and Arizona State University’s Bio-Design Institute, reflecting her international influence and collaborative approach to scientific research.

Contributions and Research Focus

Prof. Hermona Soreq’s research primarily focuses on the complex role of non-coding RNA controllers, particularly microRNAs (miRs) and transfer RNA fragments (tRFs), in brain-to-body functioning. Her groundbreaking work on acetylcholine-related pathways has combined advanced computational neuroscience with cutting-edge technologies such as sequencing, transgenic engineering, and microscopy. This multidisciplinary approach has enabled significant discoveries, including the identification of "CholinomiR" silencers that regulate anxiety, inflammation, and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Her research has also highlighted the impact of these non-coding RNAs on conditions like stroke, epilepsy, and metabolic disorders.

Accolades and Recognition

Prof. Hermona Soreq's contributions to molecular neuroscience have earned her numerous accolades and honors. She has received Honorary PhDs from prestigious institutions including the University of Stockholm, Ben-Gurion University, and Friedrich-Alexander University Erlangen-Nuremberg. Other notable awards include the Teva Founders’ Award, the Lise Meitner Alexander von Humboldt Award, and the Rappaport Prize for Biomedical Research. In 2022, she was awarded the Israeli Prime Minister’s EMET prize in Neuroscience, recognizing her exceptional contributions to the field. Soreq has also been a keynote speaker at major international conferences, further solidifying her status as a leading voice in neuroscience.

Impact and Influence

Throughout her career, Hermona Soreq has had a profound impact on the scientific community, both through her research and her mentorship. She has trained 26 faculty members who have gone on to contribute to various universities worldwide, including institutions in Jerusalem, Tel Aviv, Haifa, the Galilee, Beer Sheva, and internationally in Berkeley, Maryland, Halifax, Ann Arbor, Paris, Tours, Jena, and London. Her research on the cholinergic system’s involvement in stress, neurodegeneration, and metabolic regulation has opened new avenues for understanding and potentially treating these conditions.

Legacy and Future Contributions

Prof. Hermona Soreq’s legacy is characterized by her innovative approach to neuroscience, integrating computational and experimental methods to explore the regulatory roles of non-coding RNAs. Her work has not only advanced scientific knowledge but also has significant implications for therapeutic strategies in treating neurodegenerative and stress-related diseases. As she continues her research, Soreq is poised to make further groundbreaking discoveries that will influence the field for years to come. Her ongoing involvement in academic and scientific advisory boards, including those at Neuro-Cure Center Berlin and the ImmunoSensation Center Bonn, ensures that her expertise will continue to guide and inspire future generations of neuroscientists.

Citations

A total of 34743 citations for his publications, demonstrating the impact and recognition of her research within the academic community.

Francesca Iannone – Molecular Biology Award – Young Scientist Award

Dr. Francesca Iannone - Molecular Biology Award - Young Scientist Award

University Magna Graecia of Catanzaro - Italy 

Author Profile

Early Academic Pursuits

Dr. Francesca Iannone's academic journey began with her enrollment in the University of Calabria, where she pursued her passion for biology. Her dedication and academic excellence were evident as she graduated with top honors, receiving a grade of 110/110 cum laude for both her three-year degree and her master's degree in Biology. During her undergraduate years, she undertook internships to gain practical experience in microbiology and virology, showcasing her commitment to bridging theoretical knowledge with hands-on laboratory work. This early exposure laid a solid foundation for her future research endeavors.

Professional Endeavors

After completing her master's degree, Francesca embarked on a path of continuous learning and exploration. She secured a position as a research fellow at the University of Magna Graecia of Catanzaro, delving into the realms of proteomics and mass spectrometry. Her work focused on analyzing the peptidome of cancer-associated fibroblasts, demonstrating her commitment to cutting-edge research in cancer biology. Additionally, she served as a tutor for General Biology, sharing her expertise with the next generation of scientists.

Contributions and Research Focus On Molecular Biology Award

Dr. Francesca's research journey has been characterized by a multifaceted approach to understanding complex biological phenomena. From investigating genetic and epigenetic markers of human aging and longevity during her Ph.D. to exploring muscle-specific microRNAs in sarcopenia, her work spans various facets of clinical biochemistry and molecular biology. Notably, her contributions to the characterization of genetic factors related to age-related diseases such as Alzheimer's and atherosclerosis highlight her commitment to advancing our understanding of these conditions.

Accolades and Recognition

Throughout her academic and research career, Francesca has garnered recognition for her exemplary work. Her outstanding academic achievements, including receiving top honors for her degrees and winning prestigious research awards, underscore her dedication to excellence in the field of life sciences. Moreover, her publications in reputable journals and presentations at international conferences have solidified her reputation as a promising young scientist.

Impact and Influence

Dr. Francesca's research has the potential to make a significant impact on both scientific knowledge and clinical practice. By elucidating molecular mechanisms underlying age-related diseases and cancer progression, her work lays the groundwork for the development of novel diagnostic and therapeutic strategies. Furthermore, her commitment to mentorship and education ensures that her influence extends beyond the laboratory, inspiring future generations of scientists to pursue excellence in biomedical research.

Legacy and Future Contributions

As Francesca continues to advance in her career, her legacy as a dedicated researcher and mentor is already well-established. Moving forward, she aims to further deepen our understanding of disease mechanisms and contribute to the development of personalized medicine approaches. Through her ongoing research endeavors, mentorship activities, and collaborative efforts, Francesca remains poised to leave a lasting impact on the field of clinical biochemistry and molecular biology, shaping the future of healthcare and scientific inquiry.

Notable Publication

 

Bindhu Omana Sukumaran | Best Researcher Award | BIOCHEMISTRY 

Bindhu Omana Sukumaran | Best Researcher Award  Winner 2023  🏆

Prof Bindhu Omana Sukumaran : BIOCHEMISTRY

Congratulations to Prof. Bindhu Omana Sukumaran for receiving the Best Researcher Award at the International Research Data Analysis Excellence Awards in the field of Biochemistry. This prestigious recognition reflects your outstanding contributions to research and dedication to advancing knowledge in the field. Well-deserved honor!

Professional profile:

Early Academic Pursuits:

I began my academic journey with a strong foundation, achieving First Class in Class X under the Board of Public Examinations, Government of Kerala, in 1990. This was followed by a Pre-Degree with First Class from the University of Kerala in 1992. Subsequently, I pursued BSc in Botany (Main) with Chemistry and Zoology as subsidiaries, graduating with Distinction in 1995 from the University of Kerala. My commitment to academic excellence continued as I pursued a Master of Science in Medical Biochemistry from MAHE (Manipal Academy of Higher Education) University, where I graduated with First Class honors in 1998.

Professional Endeavors:

My professional journey took a significant turn when I embarked on a Ph.D. in Cancer Biology (Medical Biochemistry) at the Regional Cancer Centre, Thiruvananthapuram, Kerala. I successfully defended my thesis titled "Matrix Metalloproteinases in Oral Cancer" in July 2005. This comprehensive research delved into the intricate molecular mechanisms underlying the progression of Oral Squamous Cell Carcinoma (OSCC), exploring the roles of Matrix Metalloproteinases (MMPs) and their inhibitors, Tissue Inhibitor Metalloproteinases (TIMPs).

Contributions and Research Focus:

My Ph.D. work focused on understanding the functional role and clinical significance of MMPs and TIMPs in the progressing histology of oral tissue, ranging from normal to invasive oral carcinoma. The study utilized immunohistochemistry, zymography, and Western blotting techniques, revealing a gradual increase in MMP expression and gelatinolytic activity with the histologic progression of malignancy. Moreover, my research uncovered the correlation between NFκB activation and gelatinase expression, suggesting the regulatory role of NFκB in malignant transformation.

Accolades and Recognition:

During my doctoral journey, I garnered recognition for my work, presenting posters and delivering an oral presentation at prestigious events such as the 21st Annual Convention of the Indian Association for Cancer Research and the International Workshop on Cervical Cancer. These presentations highlighted the clinical significance of gelatinases in oral cancer and the activation of NFκB during oral tumorigenesis.

Impact and Influence:

The findings from my research contribute significantly to the understanding of molecular processes underlying oral cancer progression. The correlations established between MMPs, TIMPs, and NFκB activation provide valuable insights for potential prognostic markers in oral carcinoma. The impact of my work extends to the clinical analysis of surgical margins, suggesting the evaluation of MMP and TIMP proteins as new molecular-level prognostic factors.

Legacy and Future Contributions:

My research forms a foundation for future studies in the field of cancer biology, particularly in understanding the regulatory mechanisms of MMPs and the role of NFκB in malignant transformation. The implications for clinical prognostication underscore the potential for further research in developing targeted therapies for oral carcinoma.

In conclusion, my academic journey and research endeavors reflect a commitment to excellence in understanding the molecular intricacies of oral cancer, with potential implications for clinical practice and future research initiatives.

Notable Publication:

Clinical and diagnostic utility of saliva as a non-invasive diagnostic fluid: a systematic review   Cited By 374 2015 year
High expression levels of nuclear factor kappa B and gelatinases in the tumorigenesis of oral squamous cell carcinoma Cited By 98 2016 Year
Characterisation of potential milk coagulants from Calotropis gigantea plant parts and their hydrolytic pattern of bovine casein Cited By 62 2014 Year
Salivary glucose and antioxidant defense markers in type II diabetes mellitus Cited By 46 year 2014
Three phase partitioning to concentrate milk clotting proteases from Wrightia tinctoria R. Br and its characterization Cited By 29 Year 2018