Xibing Xu | Data Science | Best Researcher Award

Dr. Xibing Xu | Data Science | Best Researcher Award

Shenzhen Medical Academy of Research and Translation, China

Author Profiles

orcid

Scopus

Early Academic Pursuits 🎓

Dr. Xibing Xu’s academic journey began with a solid foundation in biological sciences, leading to his Master’s degree from Shandong University in 2012. His Master’s thesis focused on the two-component signal transduction systems of Streptomyces hygroscopicus. This foundational research sparked his interest in bacterial biology and set the stage for his doctoral studies at Sichuan University. Dr. Xu’s Ph.D. thesis, completed in 2015, centered on “Protein homeostasis regulation and ubiquitin-like systems in bacteria,” deepening his expertise in bacterial systems and protein regulation.

Professional Endeavors 💼

his Ph.D., Dr. Xu expanded his research horizons by embarking on various international and prestigious roles. In 2017-2018, he was awarded a visiting scholarship by the China Scholarship Council, enabling him to work as a visiting scholar at the Laboratoire de Microbiologie et Génétique Moléculaire (LMGM) in Toulouse, France. This experience enhanced his research capabilities and fostered a deeper understanding of bacterial molecular mechanisms. From 2020 to the present, Dr. Xu has served as a Postdoctoral Fellow at LMGM, where he leads the ANR project M-Tox, which investigates translational control by HigB1 and MenT toxins in Mycobacterium tuberculosis.

Contributions and Research Focus 🔬

Dr. Xu’s research is at the cutting edge of microbiology, focusing on bacterial growth inhibition mechanisms mediated by toxins in toxin-antitoxin systems. Specifically, his work on deleterious tRNA nucleotidyltransferase toxins, like MenT in Mycobacterium tuberculosis, has unveiled novel bacterial mechanisms that regulate translation and protein homeostasis. His research involves exploring the role of tRNA biology in bacterial growth control and the interaction between tRNA and toxin proteins, a focus that has the potential to inform future therapeutic strategies for bacterial infections. His expertise extends to RNA-seq, enzymology, and protein-RNA/DNA interactions, all of which contribute to a deeper understanding of bacterial survival and virulence.

Impact and Influence 🌍

Dr. Xu’s work has far-reaching implications in microbial Microbiologie and therapeutic development. By identifying key mechanisms that control bacterial growth through toxin-antitoxin systems, his research addresses critical challenges in combating drug-resistant bacterial infections. His investigations into tRNA biology have provided insights into how bacteria regulate protein synthesis, which could lead to the development of novel antimicrobial strategies. His innovative research has garnered attention within the scientific community, reflected in invitations to present at major international conferences such as the 29th International tRNA Conference in 2024.

Academic Citations 📚

Dr. Xu’s contributions to the field have not only enhanced scientific knowledge but have also been widely recognized and cited in academic publications. His work on toxin-antitoxin systems and tRNA nucleotidyltransferase toxins has attracted significant attention in the microbiology and biochemistry fields. As his research continues to influence studies on bacterial translation control, his citation index is expected to grow, cementing his reputation as an expert in bacterial growth regulation and antibiotic resistance mechanisms.

Technical Skills 🛠️

Dr. Xu possesses a broad array of technical skills in biochemistry and molecular biology, enabling him to conduct complex experimental research. He is proficient in RNA-seq library design and construction, protein-DNA/RNA interaction analysis, and toxin protein purification and activity assays. Additionally, he has extensive experience in cell-free transcription and translation assays, essential for studying the mechanistic details of translation regulation in bacteria. His technical prowess underpins the success of his innovative research in bacterial biology and protein homeostasis.

Teaching Experience 👨‍🏫

Dr. Xu has a strong track record in teaching and academic supervision. From 2015 to 2020, he taught various courses such as Medical Biology, Medical Genetics, and Medical Cell Biology at Henan University of Science and Technology. His teaching not only involved extensive classroom hours but also practical experimental courses, allowing students to gain hands-on experience in molecular biology techniques. Since 2024, Dr. Xu has been supervising Master’s students at the University Paul Sabatier in Toulouse, mentoring students on projects related to phage peptides and protein homeostasis in bacteria, ensuring the next generation of scientists is equipped with the necessary research skills.

Legacy and Future Contributions 🌟

Dr. Xu’s current and future research promises to continue his legacy of groundbreaking work in microbiology, particularly in the areas of bacterial toxin-antitoxin systems and translation control. As a postdoctoral fellow and researcher at LMGM, he is leading projects that could revolutionize our understanding of bacterial growth regulation, with direct applications in combating drug-resistant Mycobacterium tuberculosis. His ongoing research, mentorship, and commitment to expanding scientific knowledge will ensure that his contributions to the field of microbiology will continue to grow in impact and influence.

 Top Noted Publications 📖

Title: Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Authors: Tom J. Arrowsmith, Xibing Xu, Shangze, Ben Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, Pierre Genevaux, Tim R. Blower
Journal: Nature Communications
Year: 2024

Title: MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding

Authors: Xibing Xu, Ben Usher, C. Gutierrez, R. Barriot, T.J. Arrowsmith, X. Han, P. Redder, O. Neyrolles, T.R. Blower, P. Genevaux
Journal: Nature Communications
Year: 2023

Title: Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis

Authors: Moïse, Emmanuel Giudice, Xibing Xu, Hatice Akarsu, Patricia Bordes, Valérie Guillet, Donna-Joe Bigot, Nawel Slama, Gaetano D’Urso, Sophie Chat et al.
Journal: Nature Communications
Year: 2022

Title: ClpXP-mediated Degradation of the TAC Antitoxin is Neutralized by the SecB-like Chaperone in Mycobacterium tuberculosis

Authors: Pauline Texier, Patricia Bordes, Jyotsna Nagpal, Ambre Julie Sala, Moise Mansour, Anne-Marie Cirinesi, Xibing Xu, David Andrew Dougan, Pierre Genevaux
Journal: Journal of Molecular Biology
Year: 2021

Title: The ubiquitin-like modification by ThiS and ThiF in Escherichia coli

Authors: Xibing Xu, Tao Wang, Yulong Niu, Ke Liang, Yi Yang
Journal: International Journal of Biological Macromolecules
Year: 2019

Title: BAH1 an E3 Ligase from Arabidopsis thaliana Stabilizes Heat Shock Factor σ32 of Escherichia coli by Interacting with DnaK/DnaJ Chaperone Team

Authors: Xibing Xu, Ke Liang, Yulong Niu, Yan Shen, Xuedong Wan, Haiyan Li, Yi Yang
Journal: Current Microbiology
Year: 2018

Wenhai Shi | Predictive Modeling Innovations | Best Researcher Award

Prof. Wenhai Shi | Energy and Utilities Analytics | Best Researcher Award

Professor at Chang’an University, China

👨‍🎓Author Profiles

🎓 Early Academic Pursuits

Prof. Wenhai Shi’s academic journey is marked by a steadfast dedication to environmental sciences. He earned a Ph.D. in Soil Science (2015-2018) from the University of Chinese Academy of Sciences, Yangling, China, focusing on critical ecological processes. Prior to this, he completed his M.S. in Water Conservancy Engineering (2011-2014) at Guangxi University, Nanning, and a B.S. in Water Resources and Hydropower Engineering (2004-2008) from Xi’an University of Technology. His rigorous academic foundation laid the groundwork for his impactful career in hydrology and soil science.

💼 Professional Endeavors

Prof. Shi has built a robust professional portfolio through progressive academic and industry roles. Currently an Associate Professor at the School of Water and Environment, Chang’an University, Xi’an, he has held positions as a Lecturer and Assistant Professor in esteemed institutions, alongside early-career roles as a Laboratory Technician and Reservoir Dispatcher. These experiences have sharpened his expertise in managing large-scale water resource systems and developing ecohydrological solutions.

🌍 Contributions and Research Focus

Prof. Shi’s research addresses critical environmental challenges, including multi-scale ecohydrological processes, land surface soil and water dynamics, and the nutrient cycle in Earth’s critical zones. He is particularly renowned for investigating soil erosion mechanisms and advancing water conservation techniques. His projects, supported by prestigious bodies like the National Natural Science Foundation of China, focus on organic and inorganic carbon dynamics, hydrological simulation, and water cycle evolution in fragile ecosystems like the Loess Plateau.

🌟 Impact and Influence

Through his contributions, Prof. Shi has significantly influenced both academic and practical domains. As a reviewer for prominent international journals such as Land, Hydrology, and Remote Sensing, he ensures the dissemination of high-quality scientific knowledge. His research has enhanced understanding of hydrological systems and informed policies on sustainable water and soil management.

📚 Academic Cites

Prof. Shi is an active member of leading academic societies, including the China Soil Society and the China Society of Soil and Water Conservation, where he contributes to advancing scientific discourse. As a peer review expert for the National Natural Science Foundation of China and the Ministry of Education, his expertise shapes the future of soil and hydrology research in China and beyond.

💻 Technical Skills

With a diverse skill set, Prof. Shi excels in hydrological modeling, ecohydrological simulations, and spatial variability analysis. His technical acumen is complemented by his proficiency in research tools, project management, and data-driven decision-making in environmental sciences.

🏫 Teaching Experience

An accomplished educator, Prof. Shi has developed and taught both undergraduate and postgraduate courses, such as Soil Mechanics, Modern Hydrology, and Soil and Water Conservation. His innovative teaching methods inspire students to engage deeply with critical environmental issues. Notably, he led his students to secure the National First Prize in the 7th National College Students Water Conservancy Innovation Design Competition.

🌟 Legacy and Future Contributions

Prof. Shi’s accolades, including being recognized as a Young Academic Backbone under the Chang’an Scholars Talent Support Program, underscore his lasting contributions to academia and society. He continues to lead impactful research, mentor the next generation of environmental scientists, and innovate in teaching. Prof. Shi’s vision for the future includes enhancing sustainable practices and advancing ecohydrological resilience globally.

📖Top Noted Publications

An improved method that incorporates the estimated runoff for peak discharge prediction on the Chinese Loess Plateau
    • Authors: Shi, W.; Wang, M.; Li, D.; Li, X.; Sun, M.
    • Journal: International Soil and Water Conservation Research
    • Year: 2023
Effects of Crop Rotation and Topography on Soil Erosion and Nutrient Loss under Natural Rainfall Conditions on the Chinese Loess Plateau
    • Authors: Li, C.; Shi, W.; Huang, M.
    • Journal: Land
    • Year: 2023
An improved MUSLE model incorporating the estimated runoff and peak discharge predicted sediment yield at the watershed scale on the Chinese Loess Plateau
    • Authors: Shi, W.; Chen, T.; Yang, J.; Lou, Q.; Liu, M.
    • Journal: Journal of Hydrology
    • Year: 2022
Revised runoff curve number for runoff prediction in the Loess Plateau of China
    • Authors: Shi, W.; Wang, N.; Wang, M.; Li, D.
    • Journal: Hydrological Processes
    • Year: 2021
Predictions of soil and nutrient losses using a modified SWAT model in a large hilly-gully watershed of the Chinese Loess Plateau
    • Authors: Shi, W.; Huang, M.
    • Journal: International Soil and Water Conservation Research
    • Year: 2021

Hanna Wilczura-Wachnik | Data Analysis | Best Researcher Award

Dr. Hanna Wilczura-Wachnik | Data Analysis | Best Researcher Award

Dr. Hanna Wilczura-Wachnik at University of Warsaw, Poland

 Profiles

 Orcid Profile
 Scopus Profile
👩‍🔬 Academic Background

Hanna Wilczura-Wachnik is an adiunkt at the University of Warsaw, specializing in the study of colloids, microemulsions, and the interactions of biologically active molecules with membranes. Her research combines both theoretical and experimental approaches to advance our understanding of these complex systems.

🎓 Education

Hanna earned her MSc in 1977 from the University of Warsaw. She pursued her PhD at the same institution, which she completed in 1992. Her doctoral thesis, supervised by Prof. Teresa Kasprzycka-Guttman, was titled “The Enthalpy of Mixing in Associated Binary Systems of Pyridine and its Methyl Derivatives + n-Alkanes.”

💼 Professional Experience

Her postdoctoral research took place at the University of Tennessee under the guidance of Prof. Alexander Van Hook, focusing on liquid-liquid equilibrium (LLE) in polymer solutions. Hanna has also participated in short-term internships at various institutions, including the Technical University of Denmark, Syleyman Demirel University in Turkey, and Syddansk Universitet in Denmark. Since 2010, her research has centered on colloids, microemulsions, micellar phases, and the behavior of biologically active molecules in and through membranes.

🔬 Research Interests

Hanna’s research interests include the study of colloids, microemulsions, and micellar phases. She is particularly focused on the interfacial migration of biologically active molecules, such as antioxidants, and their interactions with models of natural membranes.

📜 Patents

Hanna is a co-inventor of Polish Patent No. 279254, issued in 1989, for a method of citric acid evolution from aqueous solutions. This patent was developed in collaboration with T. Kasprzycka-Guttman, B. Semeniuk, and M. Myśliński.

 

📖 Publication Top Noted

Interactions between quercetin and surfactants/solvents
    • Authors: Güzeloğlu, A., Bhattarai, A., Wilczura-Wachnik, H.
    • Journal: Results in Chemistry
    • Year: 2024
α-Tocopherol/AOT/alkane/water system: Calorimetric studies
    • Authors: Karpiuk, I., Wilczura-Wachnik, H., Myśliński, A.
    • Journal: Journal of Thermal Analysis and Calorimetry
    • Year: 2018
Size and diffusion phenomena of AOT/alcohol/water system in the presence of morin by dynamic light scattering
    • Authors: Bhattarai, A., Wilczura-Wachnik, H.
    • Journal: International Journal of Pharmaceutics
    • Year: 2015
Interaction between morin and AOT reversed micelles – Studies with UV-vis at 25°C
    • Authors: Bhattarai, A., Wilczura-Wachnik, H.
    • Journal: International Journal of Pharmaceutics
    • Year: 2014
Effects of surfactants on the characteristics and biosensing properties of polyaniline
    • Authors: Kuczynska, A., Uygun, A., Kaim, A., Yavuz, A.G., Aldissi, M.
    • Journal: Polymer International
    • Year: 2010
UV-vis investigation on the hydrocarbon length effect on the α-tocopherol solubility in an AOT/n-alkane/water system
    • Authors: Wilczura-Wachnik, H., Gregorczyk, I., Myslinski, A.
    • Journal: Journal of Solution Chemistry
    • Year: 2010