Prof Dr. Eric Holland, Big Data Analytics, Best Researcher Award

Prof Dr. Eric Holland at Fred Hutch Cancer Center, United States

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🌟 Summary

Eric Charles Holland is a distinguished researcher and academician specializing in neuro-oncology, currently serving as a Professor in the Human Biology Division at the Fred Hutchinson Cancer Research Center in Seattle, WA. With extensive experience spanning clinical practice and translational research, he has made significant contributions to understanding and treating brain tumors.

🎓 Education

Eric Charles Holland pursued an academic journey marked by excellence and dedication to biomedical sciences. He earned his Bachelor of Science degree in Chemistry from Miami University in Oxford, OH, from 1977 to 1981, setting a solid foundation in the fundamentals of chemical sciences. Continuing his academic pursuits, Holland completed his PhD in Biochemistry & Molecular Biology at the University of Chicago from 1981 to 1985, where he engaged deeply in the molecular mechanisms underlying biological processes. Following his PhD, he further expanded his expertise by obtaining an MD in Medicine from Stanford University between 1985 and 1990, thereby integrating clinical insights with his strong research background.

💼 Professional Experience

Eric Charles Holland is a distinguished figure in neuro-oncology with a robust professional trajectory spanning prestigious institutions and significant leadership roles. He currently holds the position of Professor in the Human Biology Division at the Fred Hutchinson Cancer Research Center in Seattle, WA, a role he has held since 2013. Previously, he served as the Director of the Nancy and Buster Alvord Brain Tumor Center at the University of Washington, Seattle, WA, from 2013 to 2019. Prior to that, he was an Attending Surgeon at Memorial Hospital for Cancer and Allied Diseases in New York, NY, from 2006 to 2013, where he also held an Associate Professorship at Cornell University from 2000 to 2006. His career is distinguished by his contributions to advancing neurosurgical techniques and his leadership in multidisciplinary research initiatives aimed at improving treatments for brain tumors.

🔬 Research Interests

Eric Charles Holland is renowned for his pioneering research in neuro-oncology, focusing particularly on gliomas, the most common type of brain tumor. His research spans from basic molecular biology to translational studies aimed at developing innovative therapies. Holland is deeply engaged in understanding the genetic and molecular mechanisms that drive glioma formation and progression, utilizing advanced techniques such as transgenic models to simulate human disease conditions. His work also delves into the complex interactions within the tumor microenvironment and their impact on treatment outcomes. Holland’s interdisciplinary approach integrates molecular biology, genetics, and clinical research, aiming to accelerate the translation of scientific discoveries into effective therapies for patients with brain tumors.

📖 Publication Top Noted

Paper Title: CSF-1R inhibition alters macrophage polarization and blocks glioma progression
    • Authors: Stephanie M Pyonteck, Leila Akkari, Alberto J Schuhmacher, Robert L Bowman, Lisa Sevenich, Daniela F Quail, Oakley C Olson, Marsha L Quick, Jason T Huse, Virginia Teijeiro, Manu Setty, Christina S Leslie, Yoko Oei, Alicia Pedraza, Jianan Zhang, Cameron W Brennan, James C Sutton, Eric C Holland, Dylan Daniel, Johanna A Joyce
    • Journal: Nature medicine
    • Year: 2013
Paper Title: A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle
    • Authors: Moritz F Kircher, Adam De La Zerda, Jesse V Jokerst, Cristina L Zavaleta, Paul J Kempen, Erik Mittra, Ken Pitter, Ruimin Huang, Carl Campos, Frezghi Habte, Robert Sinclair, Cameron W Brennan, Ingo K Mellinghoff, Eric C Holland, Sanjiv S Gambhir
    • Journal: Lecture Notes in Networks and Systems
    • Year: 2012
    •  citations: 1157
Paper Title: Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7KLF4AKT1, and SMO
    • Authors: Victoria E Clark, E Zeynep Erson-Omay, Akdes Serin, Jun Yin, Justin Cotney, Koray Özduman, Timuçin Avşar, Jie Li, Phillip B Murray, Octavian Henegariu, Saliha Yilmaz, Jennifer Moliterno Günel, Geneive Carrión-Grant, Baran Yılmaz, Conor Grady, Bahattin Tanrıkulu, Mehmet Bakırcıoğlu, Hande Kaymakçalan, Ahmet Okay Caglayan, Leman Sencar, Emre Ceyhun, A Fatih Atik, Yaşar Bayri, Hanwen Bai, Luis E Kolb, Ryan M Hebert, S Bulent Omay, Ketu Mishra-Gorur, Murim Choi, John D Overton, Eric C Holland, Shrikant Mane, Matthew W State, Kaya Bilgüvar, Joachim M Baehring, Philip H Gutin, Joseph M Piepmeier, Alexander Vortmeyer, Cameron W Brennan, M Necmettin Pamir, Türker Kılıç, Richard P Lifton, James P Noonan, Katsuhito Yasuno, Murat Günel
    • Journal: Science
    • Year: 2013
    •  citations: 856
Paper Title: The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo
    • Authors:Jason T Huse, Cameron Brennan, Dolores Hambardzumyan, Boyoung Wee, John Pena, Sara H Rouhanifard, Cherin Sohn-Lee, Carlos Le Sage, Reuven Agami, Thomas Tuschl, Eric C Holland
    • Journal: Proceedings of the National Academy of Sciences
    • Year: 2009
    •  citations: 664
Paper Title: Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
  • Authors: Nicholas J Szerlip, Alicia Pedraza, Debyani Chakravarty, Mohammad Azim, Jeremy McGuire, Yuqiang Fang, Tatsuya Ozawa, Eric C Holland, Jason T Huse, Suresh Jhanwar, Margaret A Leversha, Tom Mikkelsen, Cameron W Brennan
  • Journal: Proceedings of the National Academy of Sciences
  • Year: 2012
  •  citations: 611
Eric Holland | Big Data Analytics | Best Researcher Award

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