Xiaobin Ling | Data Science | Best Researcher Award

Dr. Xiaobin Ling | Data Science | Best Researcher Award

UMass Medical School | United States

Publication Profile

Orcid

👨‍🔬 Summary

Dr. Xiaobin Ling is a Postdoctoral Researcher at the RNA Therapeutics Institute, UMass Medical School, specializing in lncRNA structure and Cryo-EM. With a Ph.D. in Structural Biology from Fudan University, his work focuses on the mechanisms of RNA structures, molecular biology, and biophysics, with a strong emphasis on cryo-electron microscopy (Cryo-EM).

🧑‍🏫 Current Position

Postdoctoral Researcher
RNA Therapeutics Institute, UMass Medical School (2024–Present)

  • Research on RNA structures, particularly long non-coding RNAs (lncRNAs).
  • Focus on Cryo-EM techniques to elucidate RNA structural dynamics.

🎓 Education

Ph.D. in Structural Biology (2017–2023)
Fudan University, Shanghai, China

  • Research: Mechanisms and regulation of microRNA biogenesis and lncRNA structure.
    Master’s in Chemical Biology (2013–2016)
    Xiamen University, Xiamen, China
  • Research: Drug mechanisms targeting nuclear receptors.
    B.Sc. in Biotechnology (2008–2013)
    Jinggangshan University, Ji’an, China

💼 Professional Experience

Senior Research Assistant (2022–2023)
Cryo-EM Core Facility, Sichuan University, China

  • Managed operations for Titan Krios G3i, Talos Arctica G2, and JEOL1400 microscopes.
  • Applied Cryo-EM techniques for structural research.

Structural Biologist Researcher (2021–2022)
Runjia Pharmaceutical Technology Co., Ltd, Shanghai, China

  • Investigated ADAR inhibitors and their functions.

Research Assistant (2016–2017)
South University of Science and Technology of China, Shenzhen, China

  • Focused on microRNA biogenesis and its regulation.

📚 Academic Publications

Dr. Ling has authored numerous peer-reviewed publications in top journals, including Nature, Nature Structural & Molecular Biology, and Cell Reports. Notable works include:

  1. Cryo-EM structure of a natural RNA nanocage (Nature, 2025)
  2. Circularly permuted group II introns and their mechanisms (Nature Structural & Molecular Biology, 2025)
  3. Human telomeric G-quadruplex DNA binding (BBA – Gene Regulatory Mechanisms, 2023)
  4. ADAR inhibitors and their function (prepint, 2022)

💡 Technical Skills

  • Cryo-EM: Expertise in cryo-electron microscopy for RNA and protein structural analysis.
  • RNA Structure Analysis: Proficient in the study of RNA folding and dynamics.
  • Molecular Biology: Strong background in RNA and DNA manipulation, including G-quadruplexes and microRNA biogenesis.
  • Computational Tools: Skilled in structural bioinformatics and molecular modeling.

👨‍🏫 Teaching Experience

Dr. Ling has contributed to academic training and mentoring at multiple institutions, particularly in structural biology and RNA research.

🔬 Research Interests On Data Science

  • Structural biology of RNA molecules, focusing on lncRNAs and their roles in gene regulation.
  • Application of Cryo-EM to explore the structural dynamics of RNA and protein complexes.
  • Investigating RNA-related therapeutic strategies, including the use of RNA nanocages and RNA-based drug delivery systems.

 📚 Top Notes Publications

Cryo-EM structure of a natural RNA nanocage
    • Authors: Xiaobin Ling*, Dmitrij Golovenko, Jianhua Gan, Jinbiao Ma*, Andrei A. Korostelev*, Wenwen Fang*
    • Journal: Nature
    • Year: 2025 (accepted)
Structures of a natural circularly permuted group II intron reveal mechanisms of branching and back-splicing
    • Authors: Xiaobin Ling*, Yuqi Yao*, Jinbiao Ma*
    • Journal: Nature Structural & Molecular Biology
    • Year: 2025
The mechanism of UP1 binding and unfolding of human telomeric G-quadruplex DNA
    • Authors: Xiaobin Ling#, Yuqi Yao#, Lei Ding, Jinbiao Ma*
    • Journal: Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms
    • Year: 2023
DHX9 resolves G-quadruplex condensation to prevent DNA double-strand breaks
    • Authors: Juan Chen#, Xiaobin Ling#, Youshan Zhao#, Sheng Li, Manan Li, Hailian Zhao, Xianguang Yang, Chun-kang Chang, Jinbiao Ma*, Yuanchao Xue*
    • Journal: preprint
    • Year: 2022
Phytochrome B inhibits the activity of phytochrome-interacting factor 7 involving phase separation
    • Authors: Yu Xie, Wenbo Liu, Wenjing Liang, Xiaobin Ling, Jinbiao Ma, Chuanwei Yang, Lin Li*
    • Journal: Cell Reports
    • Year: 2023
Modular characterization of SARS-CoV-2 nucleocapsid protein domain functions in nucleocapsid-like assembly
    • Authors: Yan Wang#, Xiaobin Ling#, Jian Zou, Chong Zhang, Bingnan Luo, Yongbo Luo, Xinyu Jia, Guowen Jia, Minghua Zhang, Junchao Hu, Ting Liu, Yuanfeiyi Wang, Kefeng Lu, Dan Li, Jinbiao Ma*, Cong Liu*, Zhaoming Su*
    • Journal: Molecular Biomedicine
    • Year: 2023

 

Biying Fu | Machine Learning Applications | Best Researcher Award

Dr. Biying Fu | Machine Learning Applications | Best Researcher Award

Hochschule RheinMain, Germany

Professional Profile👨‍🎓

Early Academic Pursuits 📚

Dr. Biying Fu’s academic journey began with her primary and secondary education in Shanghai, China, where she developed a strong foundation in subjects like mathematics, German, English, physics, and chemistry. Her academic excellence continued through high school, culminating in an outstanding Abitur score of 1.1. She pursued a Bachelor’s degree in Electrical Engineering and Information Technology at Karlsruhe Institute of Technology (KIT), Germany, followed by a Master’s degree with a focus on Communications and Information Technology. Dr. Fu’s academic pursuits further advanced with a Ph.D. from the Technical University of Darmstadt (TUda), where she specialized in sensor applications for human activity recognition in smart environments.

Professional Endeavors 💼

Dr. Fu’s professional career began at the Fraunhofer Institute for Integrated Circuits (IGD), where she contributed significantly to the Sensing and Perception group. Over time, she expanded her expertise into the Smart Living and Biometric Technologies department, becoming a scientific employee and project leader. Her roles included innovative work on smart environments, human activity recognition, and biometric technologies. Dr. Fu has been instrumental in creating real-world applications for sensor technologies and machine learning algorithms, with notable contributions to the Smart Floor project, which focuses on indoor localization and emergency detection in ambient assisted living environments.

Contributions and Research Focus 🔬

Dr. Fu’s research has been centered around smart environments, sensor systems, and human activity recognition. Her dissertation, titled “Sensor Applications for Human Activity Recognition in Smart Environments,” examined multimodal sensor systems, including capacitive sensors, accelerometers, and smartphone microphones, for tracking physical activities and indoor localization. Her work merges signal processing, neural networks, and data generation techniques to enhance the interaction between people and machines. Her ongoing research continues to explore the intersection of artificial intelligence and explainability, contributing to the development of transparent and interpretable machine learning models.

Impact and Influence 🌍

Dr. Fu’s research in smart technologies has far-reaching implications for assistive technologies, healthcare, and the development of intuitive human-machine interactions. Her contributions to the field of human activity recognition have improved how we use sensors to monitor and analyze daily activities in smart homes and health environments. Furthermore, her involvement in interdisciplinary projects, such as optical quality control and optical medication detection, has enhanced industrial applications of computer vision and machine learning.

Academic Cites and Recognition 📖

Dr. Fu has earned recognition in both academia and industry. Her dissertation, publications, and research projects have attracted attention in top conferences and journals. Her participation in global programs like the Summer School of Deep Learning and Reinforcement Learning at the University of Alberta further emphasizes her standing in the scientific community. Additionally, Dr. Fu has been an active participant in various educational and research initiatives, such as the REQUAS project, and she continues to serve as a professor at Hochschule RheinMain, where she focuses on the emerging field of Explainable AI.

Technical Skills ⚙️

Dr. Fu possesses advanced technical skills in various programming languages, including C/C++, Java, and Python. She is highly proficient in machine learning libraries such as Scikit-Learn, TensorFlow, Keras, and PyTorch, and has hands-on experience with simulation tools like Matlab/Simulink and CST Microwave Studio. Her expertise extends to signal processing, computer vision, and the use of embedded systems for smart applications. Additionally, Dr. Fu has a strong command of version control tools like GIT and SVN, as well as project management platforms such as JIRA and SCRUM.

Teaching Experience 👩‍🏫

Dr. Fu has contributed to the academic development of students through various teaching roles. She has served as a tutor for subjects like digital technology and wave theory during her time at KIT. As a professor at Hochschule RheinMain, she currently teaches courses in smart environments, with a focus on advanced topics in Explainable AI. Her ability to communicate complex concepts clearly and her passion for fostering intellectual curiosity have made her a respected educator in her field.

Legacy and Future Contributions 🌟

Dr. Fu’s work continues to shape the future of smart environments, human-machine interactions, and explainable AI. Her research on sensor technologies and machine learning has paved the way for smarter and more intuitive technologies in healthcare, industry, and everyday life. As she continues to contribute to both academic and industry advancements, Dr. Fu’s legacy will be marked by her dedication to the development of technologies that improve human well-being and promote transparency in artificial intelligence systems. Her ongoing contributions will continue to inspire the next generation of researchers and engineers.

📖Top Noted Publications

A Survey on Drowsiness Detection – Modern Applications and Methods

Authors: Biying Fu, Fadi Boutros, Chin-Teng Lin, Naser Damer

Journal: IEEE Transactions on Intelligent Vehicles

Year: 2024

Generative AI in the context of assistive technologies: Trends, limitations and future directions

Authors: Biying Fu, Abdenour Hadid, Naser Damer

Journal: Image and Vision Computing

Year: 2024

Biometric Recognition in 3D Medical Images: A Survey

Authors: Biying Fu, Naser Damer

Journal: IEEE Access

Year: 2023

Face morphing attacks and face image quality: The effect of morphing and the unsupervised attack detection by quality

Authors: Biying Fu, Naser Damer

Journal: IET Biometrics

Year: 2022

Generalization of Fitness Exercise Recognition from Doppler Measurements by Domain-Adaption and Few-Shot Learning

Authors: Biying Fu, Naser Damer, Florian Kirchbuchner, Arjan Kuijper

Journal: Book chapter

Year: 2021

Giuliana Ramella | Artificial Intelligence | Best Researcher Award

Dr. Giuliana. Ramella | Artificial Intelligence | Best Researcher Award

National Research Council, Italy

Professional Profile 👨‍🎓

Scopus Profile

Orcid Profile

Research Gate Profile

Early Academic Pursuits 🎓

Dr. Giuliana Ramella embarked on her academic journey with a strong foundation in Physics, specializing in Cybernetics, from the University of Naples “Federico II”, Italy, where she obtained her Laurea degree in 1990. Her early career was distinguished by a fellowship granted by the Italian National Research Council (CNR) at the Institute of Cybernetics “E. Caianiello”, which marked the beginning of her deep engagement with interdisciplinary research. Her academic background was further enriched by participation in several international and national schools, covering topics from biophysics to machine vision, which laid the groundwork for her future research endeavors.

Professional Endeavors 🧑‍🔬

Dr. Ramella’s professional career at the CNR has spanned decades, beginning in 1991 with a fellowship at the Institute of Cybernetics, now known as the Institute of Applied Sciences and Intelligent Systems (CNR-ISASI). Over the years, she transitioned into permanent research roles, contributing significantly to numerous research projects. Her professional milestones include being a visiting researcher at LIAMA (Sino-French Laboratory) in Beijing, China, and overseeing major research initiatives such as those focused on image processing and the conservation of cultural heritage.

Contributions and Research Focus 🔬

Dr. Ramella’s research spans multiple fields, including image processing, artificial intelligence, neurosciences, and cultural heritage conservation. Notable contributions include leadership in projects such as CNR-IAC-CNR DIT.AD021.077 (focused on color image processing) and the Campania Imaging Infrastructure for Research in Oncology. Her work blends theoretical and practical applications, particularly in the intersection of machine learning and image analysis, demonstrating her commitment to advancing computational methods in complex scientific domains.

Impact and Influence 🌍

Dr. Ramella has made a significant impact both in Italy and internationally, particularly in the fields of biophysics, neurosciences, and cultural heritage preservation. She has led several high-profile projects, influencing the development of automated systems for monitoring and diagnosing cultural heritage, as well as data analysis systems for oncology research. Her leadership in educational coordination has also contributed to the professional development of individuals in specialized fields, including image and data management.

Academic Citations and Scholarly Recognition 📚

Throughout her career, Dr. Ramella has built a robust academic reputation, frequently cited for her work in machine learning frameworks like Pytorch, TensorFlow, and Keras, as well as her contributions to computer vision. Her involvement in international workshops and conferences further underscores her standing as a thought leader in the scientific community. Additionally, her research has had a profound effect on the fields of visual perception and neuroscience, solidifying her as a key figure in these interdisciplinary areas.

Technical Skills and Expertise 💻

Dr. Ramella is highly skilled in a range of programming languages, including Matlab, C/C++, and Python, which are essential tools for her work in data analysis and machine learning. She has a strong command over popular machine learning frameworks like Pytorch, TensorFlow, and Keras, which she applies to advanced research in image processing, signal analysis, and high-dimensional data modeling. Her technical expertise is fundamental to her contributions to automated systems in the analysis of cultural artifacts and medical imaging.

Teaching Experience 🍎

In addition to her research, Dr. Ramella has played an essential role in educational coordination. She co-led specialist courses for unemployed individuals and workers in mobility, aimed at developing technical skills for sectors like image management and building heritage monitoring. Her role in shaping the professional development of students in the fields of image analysis and information technology has left a lasting impact on both the academic and professional communities.

Legacy and Future Contributions 🔮

Looking ahead, Dr. Ramella’s legacy is poised to continue making waves in the fields of artificial intelligence and machine learning, especially in the areas of healthcare, cultural heritage conservation, and data-driven methodologies. Her ongoing involvement in projects like the Agritech research program, funded by the European Union through Next Generation EU, speaks to her future aspirations to contribute to cutting-edge research and technological advancements. Dr. Ramella’s future work promises to leave an indelible mark on interdisciplinary fields, continuing her legacy of innovation and impact across global scientific communities.

 

Top Noted Publications 📖

An Open Image Resizing Framework for Remote Sensing Applications and Beyond

Authors: Occorsio, D., Ramella, G., Themistoclakis, W.
Journal: Remote Sensing
Year: 2023

Image Scaling by de la Vallée-Poussin Filtered Interpolation

Authors: Occorsio, D., Ramella, G., Themistoclakis, W.
Journal: Journal of Mathematical Imaging and Vision
Year: 2023

Filtered Polynomial Interpolation for Scaling 3D Images

Authors: Occorsio, D., Ramella, G., Themistoclakis, W.
Journal: Electronic Transactions on Numerical Analysis
Year: 2023

 Lagrange–Chebyshev Interpolation for Image Resizing

Authors: Occorsio, D., Ramella, G., Themistoclakis, W.
Journal: Mathematics and Computers in Simulation
Year: 2022

Saliency-based Segmentation of Dermoscopic Images Using Colour Information

Author: Ramella, G.
Journal: Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization
Year: 2022